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How do you determine whether or not it’s estrogen that’s causing your symptoms?

If your answer is the use of an AI, that’s not good enough, because TRT affecting your kidneys reabsorption of sodium,, which is what commonly causes fluid retention in TRT patients, as well as blood pressure increases that could lead to anxiety.

AI’s are a bandaid and may provide relief even though estrogen is not the cause. TRT also causes plasma volume increases in addition to changing the way your body reabsorbs sodium.

The latter is under appreciated and often ignored, and estrogen is the scapegoat.