Testosterone Replacement Helps Men with Diabetes Improve Heart Health and Weight

Buy Lab Tests Online

Nelson Vergel

Founder, ExcelMale.com

Obes Res Clin Pract. 2014 Jul-Aug;8(4):e339-49. doi: 10.1016/j.orcp.2013.10.005. Epub 2013 Nov 5.

Hypogonadal obese men with and without diabetes mellitus type 2 lose weight and show improvement in cardiovascular risk factors when treated with testosterone: An observational study.

Haider A et al



Treatment of obesity with diet and exercise may have short-term success but longer-term maintenance of weight loss is less successful. Obesity is associated with a reduction of serum testosterone, and, vice versa, a reduction in serum testosterone is associated with obesity and features of the metabolic syndrome.


To investigate whether restoring serum testosterone to normal in hypogonadal obese men is beneficial with regard to weight loss and improvement of the metabolic syndrome.


A prospective registry accumulated to 181 men over five years (mean serum testosterone 10.06±1.3nmol/L (N>12.1), body mass index (BMI) ≥30kg/m(2). Of these men, 72 had diabetes mellitus type 2. All received parenteral testosterone undecanoate 1000mg/12 weeks for up to five years.


Waist circumference (cm) decreased from 111.2±7.54 to 100.46±7.1, weight (kg) from 114.71±11.59 to 93.2±8.49, BMI (kg/m(2)) from 36.72±3.72 to 30.2±2.59 (all variables statistically significant vs. baseline (p<0.0001) and each year compared to the previous year (p<0.0001)). In the 72 diabetic men, waist circumference (cm) decreased from 112.93±7.16 to 101.48±7.24, weight (kg) from 116.94±11.62 to 94.42±9.42, BMI (kg/m(2)) from 37.71±3.5 to 30.95±2.69 (all variables statistically significant vs. baseline (p<0.0001) and each year compared to the previous year (p<0.0001)). In all men serum glucose, HbA1c, lipid profiles and blood pressure improved significantly. Testosterone treatment as assessed by hemoglobin, hematocrit, serum prostate specific antigen (PSA) and occurrence of prostate cancer was acceptably safe.


Normalizing serum testosterone in obese hypogonadal men, also in those with diabetes type 2, improved their metabolic state.
Defy Medical TRT clinic doctor
Buy Lab Tests Online


bodybuilder test discounted labs
Defy Medical TRT clinic
Discounted Labs
cheap hcg viagra cialis
TRT in UK Balance my hormones
Testosterone books nelson vergel
Free Testosterone Book
Register on ExcelMale.com
Trimix HCG Offer Excelmale
Thumos USA men's mentoring and coaching
Testosterone TRT HRT Doctor Near Me
how to save your marriage

Online statistics

Members online
Guests online
Total visitors

Latest posts