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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
PEPTIDE RESULTS IN: IGF-1, testosterone, etc.
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<blockquote data-quote="mcs" data-source="post: 248260" data-attributes="member: 12"><p>Big n-1 results update.</p><p></p><p>With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - -</p><p></p><p>Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES DO WORK.</p><p></p><p>And now I have the labs to prove it.</p><p></p><p>In addition, I feel "tighter", recomp likely (no dexa to confirm yet), but can see more vascularity in extremities which is a sign of the holy grail (fat loss).</p><p></p><p><strong>GHRHs-GHRPs - I did not expect to see any results:</strong></p><p>As you can see, my IGF-I and Z score is officially in overdrive. I figure I need this in order to get enough lipolytic (fat burning) effect - for now.</p><p><img src="https://i.imgur.com/7TCkE1U.png" class="bbImage" alt="" data-url="https://i.imgur.com/7TCkE1U.png" style="" /></p><p></p><p><img src="https://i.imgur.com/gUTCche.png" class="bbImage" alt="" data-url="https://i.imgur.com/gUTCche.png" style="" /></p><p>This is an upper level for an 18 y/o and I'm 63. My baseline was 250 and now I've more than doubled that. Great for short-term (anabolism and leaning out). Bad for long-term (reduces longevity and increases tumorigenesis). But nothing else has worked thus far to recomp - not calorie restriction, not more training.</p><p></p><p>If your IGF-I is already at a supraphysiologic level, <strong><em>what benefit would the best pharma-grade GH do</em></strong>???</p><p></p><p>But how much longer is it safe staying at these supraphysiologic levels (I already complained about occasional carpal tunnel sides - same as if you take too much GH)?</p><p></p><p>Another unexpected effect: <strong>increased fasting insulin</strong> - likely from Ipamorelin. My fasting insulin level has never exceeded 8:</p><p><img src="https://i.imgur.com/iEwgYW2.png" class="bbImage" alt="" data-url="https://i.imgur.com/iEwgYW2.png" style="" /></p><p>"Ipamorelin injections will increase cell synthesis, elevate secretion levels of insulin from pancreatic tissue,"</p><p>ref: <a href="https://www.excelmale.com/forum/%22" target="_blank">https://medwinfamily.com/ipamorelin-injections/</a></p><p></p><p><strong>Kisspeptin-10 - another unexpected game changer:</strong></p><p>Total testosterone levels have a ways to go, still sub-par (basically back to baseline before I started Metformin after which it tanked my levels), FT is still in the tank as is BT. Optimizing T levels has been the bane of my existence. Due to a other health issues, I have never felt comfortable jumping on the TRT bandwagon.</p><p>I was taking 100mcg/day of KS-10 for 30 days to achieve a 40% increase in TT:</p><p></p><p><strong>01/18/2023:</strong></p><p><img src="https://i.imgur.com/r9bd6rg.png" class="bbImage" alt="" data-url="https://i.imgur.com/r9bd6rg.png" style="" /></p><p></p><p><strong>02/28/2023:</strong></p><p><img src="https://i.imgur.com/OACJl2W.png" class="bbImage" alt="" data-url="https://i.imgur.com/OACJl2W.png" style="" /></p><p></p><p>Should I double the dose and re-test in another month to see if I can get my levels optimized? I'm not ready to throw in the towel and go TRT until I've exhausted safer alternatives. Need another test to confirm this 40% boost is, in fact, due to KS-10.</p><p></p><p><strong>The healing peptides (BPC-157; TB-500) - nothing still:</strong></p><p>Improvement perhaps in the gut dept. but not in the joint/tendon/cartilage dept. I will need to go the extra mile with stem cells/PRP to regenerate the damage. Nonetheless, I still believe in BPC/TB. Perhaps the anti-inflammatory effect has somewhat reduced my CRP.</p><p></p><p><strong>Thymosin Alpha-1 - lighting up immunity - but caution to those using it:</strong></p><p>As you can see, my IL-2 receptor cytokine is slightly elevated above range:</p><p><img src="https://i.imgur.com/x7T2J6D.png" class="bbImage" alt="" data-url="https://i.imgur.com/x7T2J6D.png" style="" /></p><p></p><p>TA-1 seems to upregulate IL-2R: <a href="https://www.excelmale.com/forum/%22" target="_blank">https://pubmed.ncbi.nlm.nih.gov/2303316/</a></p><p>What else could this mean?</p><p>" Increased levels of soluble (s)IL-2R, therefore, are considered as an indication of an on-going immune response which could be used to monitor immune-mediated diseases."</p><p>ref: <a href="https://www.excelmale.com/forum/%22" target="_blank">https://www.sciencedirect.com/science/article/pii/S1521661620303910</a></p><p></p><p>My goal with TA-1 was to increase my CD8 T-cell count since they were suppressed for some unknown reason. I don't have those results yet.</p><p></p><p>What am I running?</p><p><strong>Tesamorelin: 2mg + Ipamorelin 300mcg (pm); </strong></p><p><strong>Ipamorelin/CJC-1295 blend 300mcg (am); </strong></p><p><strong>AOD-9604 333mcg (am); </strong></p><p><strong>Frag 176-191 500mcg (pm); </strong></p><p><strong>BPC-157 500mcg/day; </strong></p><p><strong>TB-500 1mg e3d; </strong></p><p><strong>just started PEG MGF 250mcg site injected in each arm (post wo); </strong></p><p><strong>Kisspeptin-10 100mcg (am); </strong></p><p><strong>Thymosin Alpha-1 1.5mg e3d. </strong></p></blockquote><p></p>
[QUOTE="mcs, post: 248260, member: 12"] Big n-1 results update. With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - - Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES DO WORK. And now I have the labs to prove it. In addition, I feel "tighter", recomp likely (no dexa to confirm yet), but can see more vascularity in extremities which is a sign of the holy grail (fat loss). [B]GHRHs-GHRPs - I did not expect to see any results:[/B] As you can see, my IGF-I and Z score is officially in overdrive. I figure I need this in order to get enough lipolytic (fat burning) effect - for now. [IMG]https://i.imgur.com/7TCkE1U.png[/IMG] [IMG]https://i.imgur.com/gUTCche.png[/IMG] This is an upper level for an 18 y/o and I'm 63. My baseline was 250 and now I've more than doubled that. Great for short-term (anabolism and leaning out). Bad for long-term (reduces longevity and increases tumorigenesis). But nothing else has worked thus far to recomp - not calorie restriction, not more training. If your IGF-I is already at a supraphysiologic level, [B][I]what benefit would the best pharma-grade GH do[/I][/B]??? But how much longer is it safe staying at these supraphysiologic levels (I already complained about occasional carpal tunnel sides - same as if you take too much GH)? Another unexpected effect: [B]increased fasting insulin[/B] - likely from Ipamorelin. My fasting insulin level has never exceeded 8: [IMG]https://i.imgur.com/iEwgYW2.png[/IMG] "Ipamorelin injections will increase cell synthesis, elevate secretion levels of insulin from pancreatic tissue," ref: [URL='https://www.excelmale.com/forum/%22']https://medwinfamily.com/ipamorelin-injections/[/URL] [B]Kisspeptin-10 - another unexpected game changer:[/B] Total testosterone levels have a ways to go, still sub-par (basically back to baseline before I started Metformin after which it tanked my levels), FT is still in the tank as is BT. Optimizing T levels has been the bane of my existence. Due to a other health issues, I have never felt comfortable jumping on the TRT bandwagon. I was taking 100mcg/day of KS-10 for 30 days to achieve a 40% increase in TT: [B]01/18/2023:[/B] [IMG]https://i.imgur.com/r9bd6rg.png[/IMG] [B]02/28/2023:[/B] [IMG]https://i.imgur.com/OACJl2W.png[/IMG] Should I double the dose and re-test in another month to see if I can get my levels optimized? I'm not ready to throw in the towel and go TRT until I've exhausted safer alternatives. Need another test to confirm this 40% boost is, in fact, due to KS-10. [B]The healing peptides (BPC-157; TB-500) - nothing still:[/B] Improvement perhaps in the gut dept. but not in the joint/tendon/cartilage dept. I will need to go the extra mile with stem cells/PRP to regenerate the damage. Nonetheless, I still believe in BPC/TB. Perhaps the anti-inflammatory effect has somewhat reduced my CRP. [B]Thymosin Alpha-1 - lighting up immunity - but caution to those using it:[/B] As you can see, my IL-2 receptor cytokine is slightly elevated above range: [IMG]https://i.imgur.com/x7T2J6D.png[/IMG] TA-1 seems to upregulate IL-2R: [URL='https://www.excelmale.com/forum/%22']https://pubmed.ncbi.nlm.nih.gov/2303316/[/URL] What else could this mean? " Increased levels of soluble (s)IL-2R, therefore, are considered as an indication of an on-going immune response which could be used to monitor immune-mediated diseases." ref: [URL='https://www.excelmale.com/forum/%22']https://www.sciencedirect.com/science/article/pii/S1521661620303910[/URL] My goal with TA-1 was to increase my CD8 T-cell count since they were suppressed for some unknown reason. I don't have those results yet. What am I running? [B]Tesamorelin: 2mg + Ipamorelin 300mcg (pm); Ipamorelin/CJC-1295 blend 300mcg (am); AOD-9604 333mcg (am); Frag 176-191 500mcg (pm); BPC-157 500mcg/day; TB-500 1mg e3d; just started PEG MGF 250mcg site injected in each arm (post wo); Kisspeptin-10 100mcg (am); Thymosin Alpha-1 1.5mg e3d. [/B] [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
PEPTIDE RESULTS IN: IGF-1, testosterone, etc.
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