Arimidex and e2/dht?

[EndoPro]

Since arimidex blocks the conversion of T to E2, would that mean that it drives dht higher since that's the other hormone T coverts to? If not, where does the t go? Does it get expelled or converted into something else?

Also, it seems like high prolactin reduces dht by 58 percent in a study I found, so would caber increase it as well?
Hyperprolactinemia and 5-alpha-reductase activity. - PubMed - NCBI

 

[Vince Carter]

Its plausible and sounds good on paper, logically it makes sense that the less you convert to E would be more Free T and/or DHT but that's not often the case in the real world. Many guys can seem to have deficient 5AR or other enzyme activity in the hormonal cascade.

 

[Cataceous]

We also have to remember that for each 10 pg/mL of estradiol production we block we are only saving about 1 ng/dL of testosterone. So under TRT, without the strong indirect effects on testosterone production, AI use should result in only relatively small changes in testosterone and DHT. I guess in theory the estradiol suppression could also reduce SHBG, which in turn could cause total testosterone to drop.