Antioxidants Improve Sex Hormone Levels

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Fifty infertile men were given supplements to improve their condition. There was also a control group of fifty men. The supplements improved hormone levels, but not sperm counts. The abstract says:

A total of 100 idiopathic infertile men aged 23-46 years were included in the study. Control group and antioxidant treatment group consisted of 50 men each. Patients in the treatment group received oral antioxidant supplement once a day. The antioxidant supplement content included L-carnitine, L-arginine, vitamin E, vitamin C, coenzyme Q, glutathione, beta-carotene, magnesium, vitamin B12, zinc, vitamin A, vitamin B6, vitamin D3, folic acid, and selenium. Reproductive hormones and sperm parameters were compared between the groups at 6 months after starting the antioxidant therapy.

Although the mean total motile sperm count (TMSC) did not increase significantly, the mean FSH (p=0.008), LH (p=0.008), and total testosterone (p=0.006) levels significantly increased from baseline to post-treatment in the treatment group. No significant differences from baseline to post-treatment were observed in the control group.

The research draws attention to the alternate treatment approaches in infertile men. Antioxidant treatment can increase the serum sex hormone levels.
Defy Medical TRT clinic doctor


Active Member
The effect was minor in men with low testosterone levels: after 6 months on the supplements, the average total testosterone increased from 379 ng/dL to 429 ng/dL which is a 13% increase.

The minor increase was most probably due to the well known Zinc (they took 7.5 mg/day) and vit. D-3 (they took 5 micrograms = ? 200 IU/day). There is no need to take a whole pharmacy of anti-oxidants.

Here is the whole article, not only the misleading abstract:


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Nelson Vergel


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