bone density

  1. L

    AI side effects?

    I had a question regarding the side effects of AI’a and can’t seem to find a consistent consensus regarding side effects. I am aware that there can be side effects from the usage of AIs, from my understanding the sides are from crashing estradiol to an unhealthy level. Most of the negatives...
  2. Nelson Vergel

    Evidence of the Effect of Low Estradiol on Fracture Risk in Men

    https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/jc.2018-00934/5094017?redirectedFrom=fulltext Evidence of a Causal Effect of Estradiol on Fracture Risk in Men Context Observational studies indicate that serum estradiol (E2) is more strongly associated with bone mineral...
  3. Nelson Vergel

    Increased SHBG and not testosterone or estradiol is associated with bone loss and fractures

    This makes sense since higher SHBG would result in lower free estradiol which is probably the main factor in bone density. They do not mention the relation between free testosterone and bone. Progressive Temporal Change in Serum SHBG, but not in Serum Testosterone or Estradiol, Is Associated...
  4. Nelson Vergel

    SHBG level may indicate risk for vertebral fractures in older men

    Peggy M. Cawthon, PhD, MPH, of California Pacific Medical Center Research Institute in San Francisco, and colleagues analyzed data from 1,463 men aged at least 65 years participating in the osteoporotic fractures in men (MrOS) study who had been randomly selected for sex hormone measurements...
  5. R

    Obesity robs major organs not blood of Vitamin A despite adequate intake

    A new Cornell University study published in Scientific Reports, shows that obesity interferes with the body’s ability to use vitamin A, even with adequate intake. http://www.futurity.org/vitamin-a-obesity-1044622-2/ Liver, kidneys and pancreas in obese mice were found to be deficient in spite...
  6. Nelson Vergel

    Men with high estradiol have stronger bones but more fat and less muscle

    Eur J Endocrinol. 2015 Aug;173(2):167-74. High aromatase activity in hypogonadal men is associated with higher spine bone mineral density, increased truncal fat and reduced lean mass. Aguirre LE Abstract OBJECTIVE: Because the aromatase enzyme catalyzes the conversion of testosterone to...
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