Search results for query: Plasma viscosity

I didn’t say they are on those doses. I used it as a study to push back against your claim regarding exposure over time. Again, I used a human study with thousands of people over years, and the group with the highest exposure had the best outcome. Meanwhile when asked for evidence to show that...

@Cataceous , since we’re building strawmen today let’s try it in reverse. Prompt and response from ChatGPT (and it should be noted I’m running these in a private browser without signing in so that replies from other conversations on the topic don’t impact response). Can an individual with...

...mechanisms: 1. Elevated fibrinogen — Fibrinogen is an acute-phase protein that rises with inflammation. It directly increases plasma viscosity and, critically, promotes rouleaux formation (red blood cells stacking like coins), which significantly increases whole blood viscosity. 2...

...fluid but its viscosity is a strong function of the proteins within. Take a look at these papers. Guess what really jacks with plasma viscosity, yep you guessed it, inflammation. Then read everything under it. People in a more inflamed state will have higher viscosity, so the healthier...

From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous testosterone stimulates red blood cell (RBC) production...

Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert doctors claiming that men on TRT don’t need to worry...

Sustained hyperviscosity, often caused by elevated hematocrit or plasma viscosity, has significant long-term effects on cardiovascular health. Below are the key findings: Long-Term Cardiovascular Effects of Sustained Hyperviscosity Increased Risk of Coronary Heart Disease (CHD): Elevated...

No shit sherlock! You very well know where the f**k I stand on this! Abe! *Implication - 54% is an arbitrary cut-off *54% is a useful, reasonable upper limit of acceptability Might want to throw this in there too! *There is no evidence that an increase of haematocrit up to and including...

I'm providing information based on the context of @Goddar statement that a lot of doctors will not allow HCT over 50% (small elevation) when other lab ranges goes all the way to 52% and the cut off being 54%. Can agree that this is an over reaction on the part of doctors? My blood pressure...

...to the extent that long-term exposure may cause harm. Why must a practitioner be cautious? When was the last time you had your plasma viscosity measured? [My concern is] more the LONGTERM vascular consequences. ... If we look at simple fluid dynamics and the laws of physics, thicker fluid...

Maybe I missed it, but is there a standard blood test that measures WBV? I found this at Quest, is this what the studies use? Quest Diagnostics: Test Directory

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824146/ The concern below would be the primary one in a patient with compromised heart function. It should be daylighted more regularly in these reviews. The effect of extra work over many years also something to consider.

https://ec.bioscientifica.com/view/journals/ec/aop/ec-24-0283/ec-24-0283.xml Therapeutic Phlebotomy: A Double-Edged Sword? Current Guidelines: "Several endocrine organizations mention therapeutic phlebotomy as a means of treating TTh–induced erythrocytosis, commonly with a hematocrit cutoff...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824146/

My HCT is 55% and hemoglobin 19.4 and blood pressure 118/71 69 bpm. My blood pressure is continuing to decline since stopping my beta blocker. It's funny really, my blood pressure numbers are better off the beta blocker. I went through the same experience, monthly phlebotomies and out of the...

Your evidence makes for good reading but in and of itself, isn't conclusive clinical study. Consequently, it adds cost, worry for perhaps very few people, and based on the more recently clinical studies on testosterone replacement, contradictory in that those show no increased risk of...

...to me until one understands the individual's particular history. Hct by itself just a part of what determines whole blood viscosity (WBV)...see plasma viscosity discussion above. 54% may result in widely different WBVs (and blood pressure, endothelial shear stress) for two different patients.

Plasma viscosity.... COVID 19 study https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251075/ Nutritional impact/discussion https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942579/ Hold the carbs and refined sugar. I am currently betting my life on modified carnivore/high protein. According to...

As usual, that's the current state of science. Again, I'm not a proponent of high hct. Not much knowledge about the impact of weightlifting, however - you won't like it - it seems that endurance training is beneficial.

...See also the Hemorheology section. Walking/sitting around all day with testosterone induced high Hct? Take a read above. If you want to roll the dice with elevated Hct, do everything in your power to keep plasma viscosity low to minimize the work your heart has to do all day/night long.

You have ruined my day. Sometimes ignorance is a bliss ;) I will try to find out what my hct was in past.

Thanks for posting. I wonder when medical practice will adopt widespread testing of whole blood viscosity [ = f(Hct, plasma viscosity,..) ] for a more complete picture of individual risk while on TRT? Or at least poor man's check of Hct plus serum viscosity...

...theories of how the body sets Hematocrit (in the absence of exogenous T use). I am still concerned with interplay between Hct and plasma viscosity with T use. I can see where using T may increase Hct and decrease plasma viscosity in the obese as they lose weight and achieve better fitness...

Thanks a lot, aloetard. That's real research, love it! Hey, I'm not a proponent of high hct. Previous generalized warnings and discussions just didn't make much sense to me. I prefer mental performance and longevity.

...You can spend a great deal of time looking into details of the interplay of Hct, vessel compliance, plasma viscosity, geometry, NO production, amount of vasodilation and their effects on wall shear stress (WSS). Make sure your whole blood viscosity (WBV) is where you want it depending on...

The theoretical derivation for arterioles was in the second link I provided (see the link under Competing effects. If you don't want to read the paper ... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014765/figure/f3/ Even in arterioles there would be very linear relationship with Hct and...

I cannot find the statement of shear stress at the vessel wall. The video you referred me to explained that there is a layer of plasma at the vessel wall and that viscosity actually decreases below 2mm diameter with still having this plasma layer.

https://emedicine.medscape.com/article/205039-overview?form=fpf Practice Essentials In secondary polycythemia, the number of red blood cells (RBCs) is increased as a result of an underlying condition. Secondary polycythemia would more accurately be called secondary erythrocytosis or...

That is encouraging; two people can have the same HCT and dramatically different whole blood viscosity. Why? They have very different plasma viscosities (inflammation, disease). Hct doesn't tell the whole story of whole blood viscosity. Congrats!

What if blood viscosity is increased but blood pressure is not affected? Are the blood vessels dilated to adapt to increased viscosity, or is some 'lubrication parameter' increased?

Extra workload in compromised individuals is a real concern. Wish more (any) youtubers would cover plasma viscosity and whole blood viscosity. https://www.excelmale.com/threads/trt-and-cardiovascular-disease.24867/post-261957