TRT Dose increased, TT and FT decrease?

_CTI_

New Member
Thread starter #1
I was on this Forum a few months back and received some excellent advice so I thought I'd bring my most recent labs because I'm not sure what's going on.
Old Protocol was 28mg IM EOD .1mg Adex .25mg Preg ED. On this protocol my TT was 944 and FT was 26.5. E2 sensitive was 16.1 These are good numbers but I was still experiencing low libido and poor sleep. Thought it might be from the low E2 so I bumped my dose by 2mg to 30mg EOD and I've attached my recent labs. This was after ~5 or 6 weeks on the 30mg EOD protocol. No other changes. As you can see my TT is now @ 650, FT @ 20.7 and E2 @ 19. Im not sure what happened except for the fact that I started noticing some pain in my testicles and thought that the extra 2mg pushed me over the edge enough to shut down whatever I was making naturally @ 28mg EOD. I know I could be completely off base here. I need to make a change but I wanted some feedback from more experienced memebers.
I'm not suffering by any means but I'm also not really experiencing the benefits like I was a month and a half ago.
Stats:
HT 6'3
WT 265
BF 22%
AGE 33
Powerlifting 3x week using linear periodization
Thanks in Advance for all your help.
 

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Vince

Moderator
#2
You are a low shbg guy, I'm sure that why your doing more frequent injections. I would say your estradiol levels are too low, how much AI are you using.
 

_CTI_

New Member
Thread starter #5
Every day dosing for an AI is too often, try dosing EOD.
I've tried dosing EOD and E3D with the Adex but I was getting weird mood swings. Maybe I didn't let it settle enough. I was thinking about dropping the AI to EOD when I get my T levels right. Trying to tackle one thing at a time.
 
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Vince

Moderator
#6
0.1mg ED. I have it compounded. How does this explain such a drastic decrease in FT and TT?
It doesn't explain your decrease, are your Labs wrong? Did you start a different vial of testosterone? I always shake my vial of testosterone before using, making sure there's no oil sitting on the bottom and making sure everything's well mixed.
 

_CTI_

New Member
Thread starter #7
It doesn't explain your decrease, are your Labs wrong? Did you start a different vial of testosterone? I always shake my vial of testosterone before using, making sure there's no oil sitting on the bottom and making sure everything's well mixed.
Same vial I was using for the previous labs so nothing new there. I used the same lab to draw that I always use as well. There really wasn't anything different about this except for the numbers and how I was feeling obviously. I don't think the lab is wrong because my hemocrit was down from my last lab, which makes sense.
 

Vince

Moderator
#8
Same vial I was using for the previous labs so nothing new there. I used the same lab to draw that I always use as well. There really wasn't anything different about this except for the numbers and how I was feeling obviously. I don't think the lab is wrong because my hemocrit was down from my last lab, which makes sense.
If you increase your dose of testosterone, you level should go up. So either you inject less or your labs are wrong. Maybe your previous labs are wrong? There's no way of telling is there.
 
Thread starter #9
If you increase your dose of testosterone, you level should go up. So either you inject less or your labs are wrong. Maybe your previous labs are wrong? There's no way of telling is there.
I guess not. If I were to increase it to get it back up to the 900-1000 range (Where I felt pretty good), how much do you think I should go up by? 10mg to 40mg EOD? More? I know people say to go slow but I don't know how slow I should take it and going up 2mg every 5-6 weeks seems like a long process.
 
#10
For your SHBG @ 16.6 your E2 is not too low. If you redo labs and I suggest that you do that since this set seems to be abnormal to the priors, keep on your protocol. But when you redo labs please if money allows add in "Estradiol, Free". In a basic sense for a low SHBG guy you should be cutting your dose, not upping it. And disregard the TT...it means nothing it's bound up and useless. Target your dosing for FT at the upper lab range, for starters. We know that low SHBG = high Free T, but this also = high Free E.
You're going to have to learn a whole lot more about low SHBG and the protocol that is associated with it.
 
#11
If you increase your dose of testosterone, you level should go up. So either you inject less or your labs are wrong. Maybe your previous labs are wrong? There's no way of telling is there.
Low SHBG...he's either pissing it out or converting it to E, most likely pissing it out every day.
 
#12
Same vial I was using for the previous labs so nothing new there. I used the same lab to draw that I always use as well. There really wasn't anything different about this except for the numbers and how I was feeling obviously. I don't think the lab is wrong because my hemocrit was down from my last lab, which makes sense.
Most guys and not to imply but most guys are not as consistent as they proclaim to be and I get indications that you are but little deviations in your day-to-day will reflect in your labs. I'm not a model for consistency but for instance I only ever inject @ 0500 every day. Precisely measure my dose, have blood drawn at the same lab, at the same time on the same day of the week, always fasted. Sounds anal retentive but being able to compare labs from one time to the next means it's important. And as we usually say when you get a set of labs or one result that is off from all your others, best to stay the course and retest to verify.
 
#13
I've tried dosing EOD and E3D with the Adex but I was getting weird mood swings. Maybe I didn't let it settle enough. I was thinking about dropping the AI to EOD when I get my T levels right. Trying to tackle one thing at a time.
You shouldn't be targeting anything above 600 ng/dL, by the time you reach this number your Free T will already be at the top of the ranges, adding more test will only cause problems with estrogen. I've got slight mood swings right now since I'm in the middle of a protocol change, each time you increase, decrease or change from twice weekly to EOD your levels will be swing for 6 weeks until finely your testosterones levels reach a stable state.

You didn't allow things to settle, you need to know how to play the TRT game or else you get discuranged without ever understanding the rules of the game. When I was on 25mg EOD it was too much, my levels went to 1000 which is terrible for a low SHBG guy. Your dosing is way off, try 15-20mg EOD.

I would like to try the AI every other injection to gauge if I'm an over-responder.
 
#14
You shouldn't be targeting anything above 600 ng/dL, by the time you reach this number your Free T will already be at the top of the ranges, adding more test will only cause problems with estrogen. I've got mood swings right now since I'm in the middle of a protocol change, each time you increase, decrease or change from twice weekly to EOD your levels will be swing for 6 weeks until finely your testosterones levels reach a stable state.

You didn't allow things to settle, you need to know how to play the TRT game or else you get discuranged without ever understanding the rules of the game.
Excellent!!
 
Thread starter #15
You shouldn't be targeting anything above 600 ng/dL, by the time you reach this number your Free T will already be at the top of the ranges, adding more test will only cause problems with estrogen. I've got slight mood swings right now since I'm in the middle of a protocol change, each time you increase, decrease or change from twice weekly to EOD your levels will be swing for 6 weeks until finely your testosterones levels reach a stable state.

You didn't allow things to settle, you need to know how to play the TRT game or else you get discuranged without ever understanding the rules of the game. When I was on 25mg EOD it was too much, my levels went to 1000 which is terrible for a low SHBG guy. Your dosing is way off, try 15-20mg EOD.

I would like to try the AI every other injection to gauge if I'm an over-responder.
I originally thought I shouldn't target anything higher either. I've attached labs with the results of my previous protocol (28mg EOD). As you can see the levels were just above normal. If those numbers and my good results held I was going try and back off the adex to see if I could get my E2 up. This last lab threw me off.
 

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