Recent content by Cataceous
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Peak vs trough testosterone level
That title is for those who don't provide proper attribution and quoting. It means there are studies demonstrating correlation, which may hint at causality, but are not definitive. I included one of several at the bottom. If you are truly interested then I can provide more of the references...- Cataceous
- Post #16
- Forum: Testosterone Basics & Questions
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Peak vs trough testosterone level
There is some evidence for such mental health issues, including anxiety. Per Grok: There is emerging evidence from psychology and related fields supporting the hypothesis that a lack of challenges or adversity—sometimes framed as excessive comfort, overprotection, or "coddling"—can contribute...- Cataceous
- Post #14
- Forum: Testosterone Basics & Questions
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Peak vs trough testosterone level
Setting aside strictly biochemical dysfunction, I think in some ways it's the opposite. We evolved to face challenges and overcome them. When everything is handed to you and you can't feel a sense of purpose or accomplishment then you get mental health issues.- Cataceous
- Post #11
- Forum: Testosterone Basics & Questions
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About to Start a New Protocol
Don't rely on the so-called direct free testosterone tests. They are useless, and the dose linearity might not be reflected in them. Instead either use equilibrium dialysis or Vermeulen calculated free testosterone. For the latter, measure SHBG and ideally albumin in addition to total...- Cataceous
- Post #60
- Forum: Testosterone Basics & Questions
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Peak vs trough testosterone level
It's human nature to strive for better. If we settled for "good enough" then we'd still be cave dwellers.- Cataceous
- Post #9
- Forum: Testosterone Basics & Questions
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Peak vs trough testosterone level
You can estimate the peak-trough ratio based on the half-life of the testosterone ester. The estimate I use for weekly injections of testosterone cypionate is 2.5, which stems from a five-day half-life. This would put your peak at over 1,500 ng/dL. However, half-lives vary among individuals, so...- Cataceous
- Post #4
- Forum: Testosterone Basics & Questions
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Federal gun laws and illegal anabolic steroids, a sword of Damocles?
I still makes me uneasy that the hundreds of seldom-enforced laws on the books make it fairly simple for government/law enforcement to make anyone miserable, even for arbitrary reasons. I suppose this wide discretion will be tolerated as long as the public perceives it being directed at the...- Cataceous
- Post #16
- Forum: The Hang Out - Where Everything Goes!
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Federal gun laws and illegal anabolic steroids, a sword of Damocles?
Don't misconstrue the original post as any kind of defense of this crackhead. Rather, it's a caution to those who don't have a daddy who can pardon them.- Cataceous
- Post #11
- Forum: The Hang Out - Where Everything Goes!
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Federal gun laws and illegal anabolic steroids, a sword of Damocles?
Where did I say I would? But spare me the pious crap about violating laws and taking risks when you're telling others to follow your lead and self-prescribe from ReliableRx. Should we call you Dr. AI instead? Says the guy going off on some tangent in response to a simple hypothetical example...- Cataceous
- Post #10
- Forum: The Hang Out - Where Everything Goes!
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Federal gun laws and illegal anabolic steroids, a sword of Damocles?
Easy for you to say Mr. AI, but most law-abiding gun owners aren't going to suspect that accepting a sleep aid could in theory result in 10 years in prison.- Cataceous
- Post #3
- Forum: The Hang Out - Where Everything Goes!
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Federal gun laws and illegal anabolic steroids, a sword of Damocles?
If you follow the news much then you may know that Hunter Biden was bitten by a federal gun law—where it's illegal to possess a gun if you use drugs illegally. Apparently the law is now being challenged in court by someone who used marijuana. I was curious and wanted to know if this applies to...- Cataceous
- Thread
- gun laws steroids
- Replies: 18
- Forum: The Hang Out - Where Everything Goes!
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About to Start a New Protocol
The week-long stabilization period is reasonable unless you're converting from a long-lived injected testosterone ester. Then the influence could last a few weeks leading to uncertainty about levels. Waiting a full three months would be good, but maybe not necessary. If you've already been on...- Cataceous
- Post #58
- Forum: Testosterone Basics & Questions
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About to Start a New Protocol
If anything it would be about the half-life rather than the SHBG "charge" time. A good rule of thumb is to allow five half-lives for stabilization. Xyosted is somewhat unusual because the lack of excipients extends its half-life to 10 days, about double that of conventional formulations of...- Cataceous
- Post #56
- Forum: Testosterone Basics & Questions
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About to Start a New Protocol
Keep in mind that transdermal testosterone is only relatively short-acting—that is, when compared to something like testosterone cypionate injections. However, it is slower than nasal gels or oral formulations. The reason why is that the skin acts as a reservoir, gradually releasing the...- Cataceous
- Post #54
- Forum: Testosterone Basics & Questions
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About to Start a New Protocol
This is correct. Maybe you're not understanding that an absorbed dose of 100 mg T is insanely high for relatively fast-acting testosterone. If done on a daily basis that's like taking 1,000 mg of testosterone cypionate every week. Or, looking at it another way, healthy young men typically make...- Cataceous
- Post #52
- Forum: Testosterone Basics & Questions
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