Recent content by Cataceous

Why do you keep parroting this nonsense when there is high quality evidence that greater consumption of plant-based foods improves health? Carnivore is a very unbalanced diet, and one of the consequences is harm to the gut microbiome. ... it's important to know what determines a healthy gut...

Methinks you need to run a sanity check on the numbers. The rat study is talking about millimolar concentrations (>100 mM/L). In contrast, serum testosterone is measured in nanomolar units. Isn't that on the order of a million times different?

Oral progesterone is decidedly unnatural. You get a large cascade of metabolites. Your premise doesn't hold for injections, but progesterone has a relatively short half-life, so you need to use it daily. Transdermal is probably ok too, but dosing is less precise and there are reports of unusual...

Something tells me there's more to those bills and expenses than food, clothing and shelter. You must forsake the rest if you really want to put people before money. If there's corruption as you allege then it is bred by the regulatory state. Libertarians might argue it's an inevitable result...

What are your priorities and tolerance for risk? If you value long-term good health above all then cut back to the initial dose, which is at least borderline physiological. There are risks in continuing with such high levels for years, but we can't be sure how significant they are. The data...

Sorry, you can't thread this needle. If these companies are greedy then so are you. You are undoubtedly making plenty more than needed to live. You could instead accept the minimum necessary and work free the rest of the time, thus prioritizing people over money. This is especially true with the...

You neglect to factor in all the government rules and regulations, which are the real reason for the big differences in price. UGLs do not need to worry about conforming to good manufacturing practices, etc. You might instead argue that big pharma doesn't mind the red tape too much because it...

I suggest waiting at least 1-2 months to see if there's movement in SHBG. The key thing is to get those androgens down and wait. Assuming you don't have a genetic predisposition to low SHBG, it probably took months to suppress yours to that degree, so expect the recovery to also take time. In...

My suspicion is that this is yet another case of "start high, go higher", very common with injections. But maybe he's an exception. It's highly questionable that a guy needs more testosterone than any man on the planet could make naturally. But sure, if he's tried a range of physiological doses...

Given that the Vermeulen free T calculation isn't showing much change, I find it to be more credible. Is this Labcorp's ultrafiltration free T test? Although it's supposed to be an accurate method, if it's as temperamental as equilibrium dialysis then it's easy to envision an erroneous...

Don't be so quick to dismiss the new doctor. It sounds like you're taking 180-200 mg of testosterone enanthate once a week, is this right? If so then you are taking about triple the testosterone the average healthy young guy makes naturally. This is not TRT. Feeling good in the short term is not...

@mchadcota: Your thread title is correct. I think @testiculus is offering the best advice, but consider dropping your testosterone dose into a physiologically realistic range over time. This is 50-100 mg of testosterone cypionate per week in divided doses. There's no evidence outside of a few...

An issue with the cited paper is the use of an immunoassay to measure estradiol. No details are given about the assay, so there is some concern that measured estradiol could be artificially inflated in those men with elevated C-reactive protein. It seems likely that systemic inflammation alone...

It's up to you to provide evidence linking these dietary studies to political taint. The fact that later controversial work invokes them is not evidence that the studies were themselves influenced. Why not do even a minute's research before making such pronouncements? Here's one of the separate...

If you think that determining relationships in complex systems is as simple as taking a few measurements then we have nothing further to discuss.