Recent content by Cataceous
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Less than 50 mg of T per week
Those are the gold-standard tests. Did you happen to have SHBG measured prior to TRT? If it used to be higher then it's another sign that this testosterone dosing is high for you, as androgens drive down SHBG. However, it's also possible that you are genetically predisposed to low SHBG. Such...- Cataceous
- Post #79
- Forum: Testosterone Basics & Questions
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How to decrease SHBG and increase free testosterone
What do your tests show? Lowering SHBG, either the actual levels, or virtually by tying it up with Proviron, does not affect free testosterone after stabilization, assuming an unchanged TRT dose. The original article should be updated to reflect this. It's covered in detail here...- Cataceous
- Post #4
- Forum: Testosterone Basics & Questions
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New Hair Loss Treatment Safer than Finasteride?: Clascoterone 5% Topical Solution
As I recall, the nightly dose was added to a PG-free Minoxidil Max product, while the morning dose was in ethyl alcohol and cyclomethicone.- Cataceous
- Post #12
- Forum: Testosterone Side Effect Management
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New Hair Loss Treatment Safer than Finasteride?: Clascoterone 5% Topical Solution
The dose was 1 mL. 50 mg/mL ~ 5% 25 mg/mL ~ 2.5%- Cataceous
- Post #10
- Forum: Testosterone Side Effect Management
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Less than 50 mg of T per week
Unless you have some other health issue this is suggesting that your dose is still too high for you. Although having total testosterone of 500 ng/dL may not seem excessive, with your daily injections you are probably maintaining this level 24 hours a day. This is an unnatural pattern, as...- Cataceous
- Post #73
- Forum: Testosterone Basics & Questions
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New Hair Loss Treatment Safer than Finasteride?: Clascoterone 5% Topical Solution
I tried clascoterone a few years back and could not tolerate it. At the time I noted a pounding heart and anxiety during two separate trials. The first trial was with 50 mg applied topically twice a day. The second was with half that dose, 25 mg. I asked the Grok AI if excess cortexolone could...- Cataceous
- Post #8
- Forum: Testosterone Side Effect Management
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TRT Review - Low SHBG, High E2, Crashing Libido
Any way you look at it the your dosing is excessive—basically double natural production. But regardless, before you head down other rabbit holes consider trying a more sensible initial strategy for treating primary hypogonadism, which I assume is what you have with one or both of the "boys"...- Cataceous
- Post #3
- Forum: Testosterone Basics & Questions
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Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene
Here's the complete answer from the AI, for what it's worth: The claim that “your FSH-producing mRNA will decay” during an 8–12-hour overnight break from pulsatile gonadorelin injections is heavily overstated and essentially false in the context of real-world manual pulsatile gonadorelin...- Cataceous
- Post #90
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Pituitary restart while on TRT: promising initial results with GnRH plus enclomiphene
@KNDyMan: Your contributions are welcome. A few comments: I am also skeptical of the weekly, high-dose gonadorelin protocols. I have not seen reports on what the subjective results are like. Royal Medical Center did demonstrate high levels of the gonadotropins shortly after the injections...- Cataceous
- Post #85
- Forum: hCG, Clomid & Others for Fertility, PCT or Low T
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Lowering trt dose/ increasing frequency of injections question
I think 65 mg is a reasonable start. Be aware that dose reductions can trigger temporary symptoms of hypogonadism even when levels are adequate. Using proportionality does put total testosterone at weekly troughs in the mid 400s ng/dL with this protocol. As an aside, it is technically more...- Cataceous
- Post #30
- Forum: Testosterone Basics & Questions
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Lowering trt dose/ increasing frequency of injections question
Looking back at your posts I see that you use Testoviron. This includes benzyl benzoate, which does have anti-microbial properties, though it's not as effective as benzyl alcohol. It would not be difficult to purchase some benzyl alcohol and sterile vials to convert the ampules to multi-dose...- Cataceous
- Post #28
- Forum: Testosterone Basics & Questions
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GHK-cu and DHT
I'm not sure about rapid, acute effects. However, I'm now wondering if the ostensible improvements in cognition I experienced are attributable to the GHK-Cu rather than the exogenous GnRH, as I had originally supposed. Or perhaps a synergy. What makes me consider the possibility is that an AI...- Cataceous
- Post #38
- Forum: General Peptide Use & Information
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Lowering trt dose/ increasing frequency of injections question
With the caveat that these are very crude estimates based on typical absorption rates and should only be used to get a general sense of things: Your trough testosterone of 525 ng/dL with once-weekly injections means we might estimate your weekly peak total testosterone (TT) as 1,300 ng/dL and...- Cataceous
- Post #26
- Forum: Testosterone Basics & Questions
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My Father is 70 years old and we just got his labs done. I'd like your advice
His Vermeulen calculated free testosterone is 9.8 ng/dL. It's considered borderline, but not really into hypogonadal territory. I would not be looking at that first as a cause of his issues, particularly if sexual function is ok. Of course being diabetic harms sexual function on its own. Having...- Cataceous
- Post #3
- Forum: Testosterone Basics & Questions
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Second Opinion on Restarting TRT (Primary Hypogandism)
Was this at 31 days on TRT, or further along? If only a month then suppression would likely progress. Three months would be harder to explain, though it sounds like reduced levels of LH/FSH/GnRH/kisspeptin were still taking a toll on sexual function. I personally have found that restoring some...- Cataceous
- Post #7
- Forum: Testosterone Side Effect Management
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