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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What is TRT and What is NOT TRT
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<blockquote data-quote="Cataceous" data-source="post: 195407" data-attributes="member: 38109"><p>I came across this <a href="https://pubmed.ncbi.nlm.nih.gov/29855071/" target="_blank">reference</a>, suggesting independent importance of free testosterone. They used the Vermeulen calculation:</p><h3><p style="margin-left: 20px"><p style="margin-left: 20px">Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism</p> </p> </h3> <p style="margin-left: 20px">...</p> <p style="margin-left: 20px"><strong>Results: </strong>... [Low total testosterone and low free testosterone], but not [low total testosterone and normal free testosterone], was associated with new/worsened sexual symptoms, including low desire ..., erectile dysfunction ... and infrequent morning erections ... .</p> <p style="margin-left: 20px"></p> <p style="margin-left: 20px"><strong>Conclusions: </strong>These longitudinal data demonstrate the importance of FT in the diagnosis of hypogonadism in obese men with low TT and SHBG. The concurrent fall in TT and FT identifies the minority (27.3%) of men with hypogonadal symptoms, which were not present in the majority developing low TT with normal FT.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 195407, member: 38109"] I came across this [URL='https://pubmed.ncbi.nlm.nih.gov/29855071/']reference[/URL], suggesting independent importance of free testosterone. They used the Vermeulen calculation: [HEADING=2][INDENT][INDENT]Symptomatic androgen deficiency develops only when both total and free testosterone decline in obese men who may have incident biochemical secondary hypogonadism[/INDENT][/INDENT][/HEADING] [INDENT]...[/INDENT] [INDENT][B]Results: [/B]... [Low total testosterone and low free testosterone], but not [low total testosterone and normal free testosterone], was associated with new/worsened sexual symptoms, including low desire ..., erectile dysfunction ... and infrequent morning erections ... .[/INDENT] [INDENT][/INDENT] [INDENT][B]Conclusions: [/B]These longitudinal data demonstrate the importance of FT in the diagnosis of hypogonadism in obese men with low TT and SHBG. The concurrent fall in TT and FT identifies the minority (27.3%) of men with hypogonadal symptoms, which were not present in the majority developing low TT with normal FT.[/INDENT] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
What is TRT and What is NOT TRT
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