ABSTRACT Background Sebum physiology and its contributions to acne vulgaris (AV) pathophysiology have been long debated. Within the pilosebaceous unit, androgens drive sebocyte production of sebum, comprising mono-, di-, and triglycerides (the latter converted to fatty acids); squalene...
Background Acne vulgaris commonly affects adults, adolescents, and preadolescents aged 9 years or older. Objective The objective of this study was to provide evidence-based recommendations for themanagement of acne. Methods A working group conducted a systematic review and applied the...
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