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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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<blockquote data-quote="tareload" data-source="post: 189362"><p>Great point on the direct free T RIA measurement. From the same paper:</p><p></p><p>[ATTACH=full]11205[/ATTACH]</p><p></p><p></p><p>[ATTACH=full]11206[/ATTACH]</p><p></p><p>We still have either an accuracy or bias issue in the measurement of free T by equilibrium dialysis. The vast majority of data presented in the literature indicates both linear Vermeulen and Tru-T way overestimate free T measured by equilbrium dialysis. Vermeulen overestimates less.</p><p></p><p>Whether the free hormone hypothesis is correct or not, my takeaway is there's a serious issue with measuring free testosterone between labs and assays (all employing "gold standard" ED). Before you validate the fitness of a model, you have to validate the accuracy of the data.</p></blockquote><p></p>
[QUOTE="tareload, post: 189362"] Great point on the direct free T RIA measurement. From the same paper: [ATTACH type="full"]11205[/ATTACH] [ATTACH type="full"]11206[/ATTACH] We still have either an accuracy or bias issue in the measurement of free T by equilibrium dialysis. The vast majority of data presented in the literature indicates both linear Vermeulen and Tru-T way overestimate free T measured by equilbrium dialysis. Vermeulen overestimates less. Whether the free hormone hypothesis is correct or not, my takeaway is there's a serious issue with measuring free testosterone between labs and assays (all employing "gold standard" ED). Before you validate the fitness of a model, you have to validate the accuracy of the data. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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