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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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<blockquote data-quote="madman" data-source="post: 151450" data-attributes="member: 13851"><p><strong><span style="color: rgb(184, 49, 47)">Again the proper way to do a comparison would be to use the measured methods:</span></strong></p><p></p><p><strong><span style="color: rgb(251, 160, 38)">gold standard Equilibrium Dialysis</span></strong> or <span style="color: rgb(250, 197, 28)"><strong>Ultrafiltration </strong></span>results compared to the <span style="color: rgb(26, 188, 156)"><strong>direct immunoassays</strong></span>.....than you would see the big difference and how inaccurate the direct immunoassay and tracer analog testing methods are when compared to the gold standard.</p><p></p><p>I should have been more specific as in many examples I am showing the results using members <strong><span style="color: rgb(26, 188, 156)">direct immunoassays</span> (measured) </strong>compared to the newer <span style="color: rgb(0, 0, 0)"><strong>calculated </strong></span><span style="color: rgb(184, 49, 47)"><strong>TruT </strong></span>method <strong><span style="color: rgb(184, 49, 47)">only because the accuracy of the TruT calculated method is on par with results using the </span></strong><span style="color: rgb(251, 160, 38)"><strong>measured gold standard Equilibrium Dialysis.</strong></span></p><p></p><p>By using the newer calculated <span style="color: rgb(184, 49, 47)"><strong>TruT </strong></span>method I am basically showing them what their FT levels would truly be if they had the more accurate gold standard Equilibrium Dialysis done.</p><p></p><p>So when using the <span style="color: rgb(184, 49, 47)"><strong>TruT </strong></span>calculated method results .....they should be very similar to the results one would get when testing using the measured gold standard Equilibrium Dialysis.</p><p></p><p>Problem is most are just getting the cheap inaccurate direct immunoassay for FT as oppose to the more accurate testing methods Equilibrium Dialysis or Ultrafiltration....so they can never compare the direct immunoassay results to the gold standard Equilibrium Dialysis to truly see the difference in what their FT levels truly are.</p><p></p><p>You have the results from the measured direct immunoassay and using the newer calculated TruT.....you would now need to test FT again using the measured Equilibrium Dialysis or Ultrafiltration and than compare the results with the direct immunoassay and you will see the difference between the measured methods and when looking at overall results the TruT calculated FT results should be very close to Equilibrium Dialysis FT results as oppose to the direct immunoassay results.</p><p></p><p></p><p></p><p></p><p></p><p></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">April 22/2019</span></strong></p><p></p><p><a href="https://www.excelmale.com/forum/goto/post?id=146452" target="_blank">Blackhawk said:</a></p><p>Mind blown. I am utterly confused.</p><p>...</p><p>When converted that's 351.6 pg/ml compared to direct at 18.8 pg/ml</p><p></p><p>So are we looking at an entire revamp of the direct assay pg/ml reference? Different method, utterly different range?</p><p></p><p></p><p>Cataceous replied:</p><p></p><p><strong><span style="color: rgb(26, 188, 156)">"The direct free T assays should not be used, period. Not only are they on an entirely different scale, by an order of magnitude, but they also do not correlate well with either </span><span style="color: rgb(251, 160, 38)">equilibrium dialysis </span></strong><span style="color: rgb(0, 0, 0)">or</span><strong> <span style="color: rgb(250, 197, 28)">ultrafiltration.</span><span style="color: rgb(26, 188, 156)"> In short they are just plain inaccurate.</span></strong><span style="color: rgb(184, 49, 47)"> <strong>The TruT calculation correlates well with the high-quality tests and is on virtually the same scale. The Vermeulen free T calculation correlates well with the good tests, but is effectively on a lower scale"</strong></span></p></blockquote><p></p>
[QUOTE="madman, post: 151450, member: 13851"] [B][COLOR=rgb(184, 49, 47)]Again the proper way to do a comparison would be to use the measured methods:[/COLOR][/B] [B][COLOR=rgb(251, 160, 38)]gold standard Equilibrium Dialysis[/COLOR][/B] or [COLOR=rgb(250, 197, 28)][B]Ultrafiltration [/B][/COLOR]results compared to the [COLOR=rgb(26, 188, 156)][B]direct immunoassays[/B][/COLOR].....than you would see the big difference and how inaccurate the direct immunoassay and tracer analog testing methods are when compared to the gold standard. I should have been more specific as in many examples I am showing the results using members [B][COLOR=rgb(26, 188, 156)]direct immunoassays[/COLOR] (measured) [/B]compared to the newer [COLOR=rgb(0, 0, 0)][B]calculated [/B][/COLOR][COLOR=rgb(184, 49, 47)][B]TruT [/B][/COLOR]method [B][COLOR=rgb(184, 49, 47)]only because the accuracy of the TruT calculated method is on par with results using the [/COLOR][/B][COLOR=rgb(251, 160, 38)][B]measured gold standard Equilibrium Dialysis.[/B][/COLOR] By using the newer calculated [COLOR=rgb(184, 49, 47)][B]TruT [/B][/COLOR]method I am basically showing them what their FT levels would truly be if they had the more accurate gold standard Equilibrium Dialysis done. So when using the [COLOR=rgb(184, 49, 47)][B]TruT [/B][/COLOR]calculated method results .....they should be very similar to the results one would get when testing using the measured gold standard Equilibrium Dialysis. Problem is most are just getting the cheap inaccurate direct immunoassay for FT as oppose to the more accurate testing methods Equilibrium Dialysis or Ultrafiltration....so they can never compare the direct immunoassay results to the gold standard Equilibrium Dialysis to truly see the difference in what their FT levels truly are. You have the results from the measured direct immunoassay and using the newer calculated TruT.....you would now need to test FT again using the measured Equilibrium Dialysis or Ultrafiltration and than compare the results with the direct immunoassay and you will see the difference between the measured methods and when looking at overall results the TruT calculated FT results should be very close to Equilibrium Dialysis FT results as oppose to the direct immunoassay results. [B][COLOR=rgb(184, 49, 47)]April 22/2019[/COLOR][/B] [URL='https://www.excelmale.com/forum/goto/post?id=146452']Blackhawk said:[/URL] Mind blown. I am utterly confused. ... When converted that's 351.6 pg/ml compared to direct at 18.8 pg/ml So are we looking at an entire revamp of the direct assay pg/ml reference? Different method, utterly different range? Cataceous replied: [B][COLOR=rgb(26, 188, 156)]"The direct free T assays should not be used, period. Not only are they on an entirely different scale, by an order of magnitude, but they also do not correlate well with either [/COLOR][COLOR=rgb(251, 160, 38)]equilibrium dialysis [/COLOR][/B][COLOR=rgb(0, 0, 0)]or[/COLOR][B] [COLOR=rgb(250, 197, 28)]ultrafiltration.[/COLOR][COLOR=rgb(26, 188, 156)] In short they are just plain inaccurate.[/COLOR][/B][COLOR=rgb(184, 49, 47)] [B]The TruT calculation correlates well with the high-quality tests and is on virtually the same scale. The Vermeulen free T calculation correlates well with the good tests, but is effectively on a lower scale"[/B][/COLOR] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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