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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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<blockquote data-quote="madman" data-source="post: 145417" data-attributes="member: 13851"><p><strong><span style="color: rgb(184, 49, 47)">*</span>However, the relationship between cFT-Vermeulen and measured free T was found to be linear and independent of <span style="color: rgb(184, 49, 47)">serum T, albumin and SHBG concentrations.</span></strong></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">*</span>The <span style="color: rgb(184, 49, 47)">lack of reliance on SHBG in the Vermeulen equation</span> was thought to be <span style="color: rgb(184, 49, 47)">strength of the cFT-Vermeulen </span>since assessment of free T is especially important in patients at the extremes of the SHBG concentration range. </strong></p><p></p><p><strong><span style="color: rgb(184, 49, 47)">*</span>The <span style="color: rgb(184, 49, 47)">bias</span> is probably due<span style="color: rgb(0, 0, 0)"> to </span><span style="color: rgb(41, 105, 176)">imperfect estimations </span>of the <span style="color: rgb(41, 105, 176)">association constants</span> for <span style="color: rgb(41, 105, 176)">the binding of T to SHBG and albumin</span>, as discussed above, and this would <span style="color: rgb(184, 49, 47)">need to be allowed for </span>when comparing different methods for cFT.</strong></p></blockquote><p></p>
[QUOTE="madman, post: 145417, member: 13851"] [B][COLOR=rgb(184, 49, 47)]*[/COLOR]However, the relationship between cFT-Vermeulen and measured free T was found to be linear and independent of [COLOR=rgb(184, 49, 47)]serum T, albumin and SHBG concentrations.[/COLOR][/B] [B][COLOR=rgb(184, 49, 47)]*[/COLOR]The [COLOR=rgb(184, 49, 47)]lack of reliance on SHBG in the Vermeulen equation[/COLOR] was thought to be [COLOR=rgb(184, 49, 47)]strength of the cFT-Vermeulen [/COLOR]since assessment of free T is especially important in patients at the extremes of the SHBG concentration range. [/B] [B][COLOR=rgb(184, 49, 47)]*[/COLOR]The [COLOR=rgb(184, 49, 47)]bias[/COLOR] is probably due[COLOR=rgb(0, 0, 0)] to [/COLOR][COLOR=rgb(41, 105, 176)]imperfect estimations [/COLOR]of the [COLOR=rgb(41, 105, 176)]association constants[/COLOR] for [COLOR=rgb(41, 105, 176)]the binding of T to SHBG and albumin[/COLOR], as discussed above, and this would [COLOR=rgb(184, 49, 47)]need to be allowed for [/COLOR]when comparing different methods for cFT.[/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
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