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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
3 Reasons for "Deca D*ck"
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<blockquote data-quote="DS3" data-source="post: 175982" data-attributes="member: 18514"><p>Another good study with interesting results.</p><p></p><p>"DHT = 1.00; nortestosterone = 0.32-0.4; testosterone = 0.1-0.2; DHN = 0.12....It is concluded that testosterone and 19-nortestosterone (which are equally good substrates for 5 alpha-reductase) are converted in the seminal vesicles to metabolites, of which DHT exhibits an affinity to the androgen receptor nearly one order of magnitude higher than that of DHN. On the other hand, in skeletal muscles that are practically devoid of 5 alpha-reductase activity, the 3-fold higher affinity of nortestosterone to the receptor, expectedly, results in a myotropic activity that is superior to that of testosterone."</p><p></p><p>So what is interesting and affirming from this study is that DHT has a significantly higher binding affinity for the androgen receptor compared to DHN, which demonstrates why DHT has a much strong ability to burn fat. However, DHN's effect in the skeletal muscle demonstrates nandrolones' higher myotropic effects. This study does much to reaffirm the lower androgenicity and higher anabolism experienced with nandrolone, and vice-versa for testosterone.</p><p></p><p>In addition to these physiological effects, both DHT and DHN will cross the blood-brain barrier (as testosterone and nandrolone both readily do) and cause varying neuropsychiatric effects; one of these effects potentially being a reduced feeling of manliness (with DHN compared to DHT). This is speculative as the brain is a highly complex organ and no studies regarding T & N investigate these effects. However, DHT is noted in the literature to bring about enhanced mood, libido, and cognitive function, so we do know that DHN plays an important role throughout the CNS.</p><p></p><p>I also like the 2nd study you posted regarding nitrogen retention. I can say from person experience that 125 mg of Deca (in addition to TRT) created significantly more nitrogen retention my muscles than did adding 125 mg of more T to my TRT. Less than 100 mg did very minimal. 50 did nothing that could be visually seen or felt (e.g. muscle fullness).</p></blockquote><p></p>
[QUOTE="DS3, post: 175982, member: 18514"] Another good study with interesting results. "DHT = 1.00; nortestosterone = 0.32-0.4; testosterone = 0.1-0.2; DHN = 0.12....It is concluded that testosterone and 19-nortestosterone (which are equally good substrates for 5 alpha-reductase) are converted in the seminal vesicles to metabolites, of which DHT exhibits an affinity to the androgen receptor nearly one order of magnitude higher than that of DHN. On the other hand, in skeletal muscles that are practically devoid of 5 alpha-reductase activity, the 3-fold higher affinity of nortestosterone to the receptor, expectedly, results in a myotropic activity that is superior to that of testosterone." So what is interesting and affirming from this study is that DHT has a significantly higher binding affinity for the androgen receptor compared to DHN, which demonstrates why DHT has a much strong ability to burn fat. However, DHN's effect in the skeletal muscle demonstrates nandrolones' higher myotropic effects. This study does much to reaffirm the lower androgenicity and higher anabolism experienced with nandrolone, and vice-versa for testosterone. In addition to these physiological effects, both DHT and DHN will cross the blood-brain barrier (as testosterone and nandrolone both readily do) and cause varying neuropsychiatric effects; one of these effects potentially being a reduced feeling of manliness (with DHN compared to DHT). This is speculative as the brain is a highly complex organ and no studies regarding T & N investigate these effects. However, DHT is noted in the literature to bring about enhanced mood, libido, and cognitive function, so we do know that DHN plays an important role throughout the CNS. I also like the 2nd study you posted regarding nitrogen retention. I can say from person experience that 125 mg of Deca (in addition to TRT) created significantly more nitrogen retention my muscles than did adding 125 mg of more T to my TRT. Less than 100 mg did very minimal. 50 did nothing that could be visually seen or felt (e.g. muscle fullness). [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
3 Reasons for "Deca D*ck"
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