1. #1

    Best time of day for hCG monotherapy injections?

    After 9 years of Clomid use, I'm switching to hCG.

    I'm doing 750 units 2x a week (Monday and Thursday). Is it better to inject in the morning, or evening? I'm assuming evening, since natural testosterone production tends to occur during sleep.

    I read a few other threads on this topic but was curious to see if there's a general consensus.

    I'll be happy to update with my thoughts on Clomid monotherapy v hCG after I get some labs.

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  3. #2
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    For me...HCG mono drove my E2 through the roof. Then the AI game begins. For me, this was not a sustainable HRT option.

    If you still try it, I would suggest talking to your Doc about more frequent & smaller doses as an option to consider.

  4. #3
    Member FeelingLost's Avatar
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    I am not on mono but I inject 400iu twice a week Monday and Thursday. I inject first thing in the morning.
    To be honest I don't think it matters. What is the half life of HCG? Doesn't it take a while to get up to a therapeutic lvl?

    If you are secondary an can get your boys working again E2 could be an issue. Looking forward to reading about your next blood test.
    Best of luck.

  5. #4
    Moderator Vince's Avatar
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    I believe the 1/2 life of HCG is about about 30 hours.

    Nelson has a good thread on HCG.
    The Use of HCG to Prevent / Reverse Testicular Shrinkage and Preserve Fertility
    https://www.excelmale.com/showthread...erve-Fertility
    I am not a medical practitioner. Any suggestions I provide are not medical recommendations and are just my opinions. Please consult with your physician on any matters concerning your health.

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