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I’ve been on HCG mono for some time now and my labs have recently looked strong. (On 600iu EOD and .5mg Anastrazole a week, my labs have been T in the low 600s and E2 in the mid/high 30s. My SHBG is about 20.) Prolactin is normal. While I have slimmed down alot on this protocol, I have been...

For so long we used to believe that “low-normal” estrogen was optimal in men, which seemed to based off of cartoonish representations of hormones rather than scientific evidence. Of course, we now know that low-normal estrogen is not only not optimal, but potentially unhealthy. Will we soon...

I posted something like this in a different thread but I think it probably needs its own thread: I often hear posters claim that Clomid gave them “perfect” labs but they felt no better. However, these posters often only include their TT numbers and not their E2 numbers. When asked what their E2...

Is there any research to suggest that “high-normal” levels are best for overall health and sexual function? Everyone always talks about how men should aim for “high-normal” levels but I have always felt better just in the “mid-normal” range. I feel like advocating for “high normal” T levels...

Based on my readings, it seems like T mono protocols often do not require an AI, whereas HCG mono protocols often do require an AI. Where do T+HCG protocols stand relative to those two protocols? Is 1000iu a week of HCG generally enough to necessitate the use of an AI in conjunction with say...

I am nervous my T-cypionate is losing potency based on how I am injecting. I’ve been using insulin syringes to both draw and inject testosterone. Since it is hard to draw up the testosterone with the insulin syringe, I generally pull my plunger back much higher than my intended dose (to .4...

There is generally no fear of women permanently losing their fertility when they start birth control, even though birth control (generally a mix of estradiol and progesterone) is intended to shut down a woman’s HPG axis, leads to the lack of ovarian stimulation, and leads to ovarian shrinkage...

Did doctors get kickbacks when they (could) prescribe HCG from Empower/Hallandale? People always said that TRT clinics “made a fortune” when dispensing HCG. So was there any system by which HCG could be prescribed and the doctor could make a profit?

I’ve been very interested in Dr. Saya’s fertility rankings posted below (HCG Monotherapy to Clomid Ratio For Fertility): 1. Clomid/SERM treatment 2(A). HCG + HMG (or lyophilized FSH) 2(B). Baseline no treatment (no HPTA suppression via TRT, AAS, HCG mono, etc) - assuming no significant degree...

Has anyone here visited Dr. Jed Kaminetsky (Urologist) in NY for HRT/TRT? I am curious to hear people’s thoughts about him.

It seems like some users don’t buy into the notion that low shbg is cause to inject more often. But the math is relatively simple: take two men: Man A has a FT percentage of 2% and Man B has a FT percentage of 3%. If both take 100mg of T a week, and each has a TT peak of 1000 and trough of 500...