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That's not true or proven and none of that has ever been resolved that elevated a guys SHBG to whatever 'normal' actually is...??? Note as well most of what people think is associated with low SHBG is made up lazy people diseases; metabolic syndrome/adrenal fatigue/pre-diabetes. What has been...

the break point in sterility and integrity of the syringe, contamination of the medication is probably much further down the line in the area of more than a week, perhaps. None of that has been proven though. I load no more than 5 syringes at a time to cover my week.

Nothing wrong at all.

Having my trough E2 mirror my SHBG of ~12 changed a lot of things for the better for me personally so I've been interested in where that lands for other guys.

I don't think that there are targets such as you're asking

Nothing I've done for 5 years in dose adjustments and all that has moved me from ~12. The best way to manage low SHBG is that it's not a condition. Ever notice that high SHBG isn't associated with any of these boogaloo nasty and often made-up conditions (made up as in synonymous with lazy...

There's no reason to lower IGF-1 it is not the cause of any of your concerns, SHBG or otherwise.

I think that you should reduce your dose from 180mg and consider EOD dosing, having your Free T below the lab range in a trough such as you do might be a problem. Maybe 30mg EOD. Your low SHBG, like me, and it just means, basically, that you process out the T very quickly it's why you're on a...

I like to see where peoples SHBG and the E that they report as being best for them where those two factors intersect and how much disparity there is.

Very interesting...thanks for taking the time. Seems to confirm that when guys have a poor experience with HCG that it could be Estrogen. What is your SHBG and which point would you say you felt your best???

I'm remembering now why I had you on my blocked list for a long time and had to prevent you from sending me PM's.

My DHT is way over the lab range on this dose of cream. On a 16-79 scale (Quest) my base line is no more than 40. but ~2hrs post injection I'm over a 100, my last DHT was 155.

12.5mg AM and 12.5mg PM No AI No HCG

Added blood flow will get muted when E goes up, if that's indeed what is happening on either account.

was... 8mg/Cyp/D (AM) .25mg AI/D (AM) 12.5mg cream/Scrotum AM and again PM

my cream (Empower) is 50mg/mL and dispenses 1/4mL per click so I'm using 1 click or 12.5mg in the AM and again PM

I won't disagree with you about HCG but I'm curious to what this means (bold). Curious if you're looking at a number on a test as the sole indicator and if so what your numbers really say.

If there was a ratio of hormones, "a specific balance between Free t, dht and e2" these forums would pretty much dry up with guys having no problems at all because they could hit a T:E ratio and be just perfect, no libido complaints...none of that. You're tenure on this forum is fraught with...

Thanks @eli Ive come to realize that my Estrogen problem while low SHBG as I am, has a direct correlation to injections...entire time ive been on injections there's been an E problem. And, i've had a DHT problem, too, reason I've been using the cream. I have a set of lab results I'm waiting on...

This is more evidence that you have no idea what you're talking about here.

ratio's are made up that's why you can't find any solid evidence. Guys make up this and that as it applied to THEM but with all of this it's very very difficult to spread out what works for one guy and apply it to others. For instance the T:E ration of 14-20 resulted in ED, severe body acne...

HCG often gets this kind of subjective response which can be construed as Estrogen. the direct stim of the testes like HCG makes can translate to Estrogen and if you're sensitive to Estrogen it can be a real problem. I would definitely not use the DHEA and/or Preg, at this time, I tend to not...

Just put him on ignore/block and go with your life.

Too on this forum peptides and those types of things really aren't well represented or under represented on this forum, this forum's population isn't really in to these things besides a few guys here and there and then they drift away some where else where what they want to do is more welcomed...

I think he's basically answered his own question here

how that works in your own body, I don't think any one can say.

Which is wrong...you shoot on M/W/F your labs should be taken one of those mornings.

You really need to consider your ability to help guys and probably just refrain from posting because this is the second time in as many days that you're not even close to being helpful here.

If you want to get strictly IM and not shallow IM then I'd go longer than 1/2" but again depends on how lean you are.

Where are you applying the cream on your body? I agree above with @S1W that your numbers for 3.5hrs post application are very poor. @pyater

relative to your injections when was your blood drawn? I can tell that you did it wrong with how high your numbers are, not in the trough.