Testosterone Measurement While Treating Prostate Cancer: Which Test and When?

Nelson Vergel

Founder, ExcelMale.com
Thread starter #1
The Canadian consensus statement recommends achieving a serum testosterone level of less than 0.7nmol/l as there appears to be an associated clinical benefit9. Additional recommendations include regular monitoring of testosterone and PSA levels throughout the first year of ADT treatment, using validated LC-MS/MS methods for testosterone assays at low testosterone levels (<0.7 nmol/l) (0r 20 ng/dL)

In conclusion, lower testosterone levels correlate with better freedom from CRPC. Breakthrough testosterone levels above 1.7 nmol/l have higher rates of failure. Testosterone levels should be assessed periodically to ensure castrate levels (every 3- months), with confirmation of lab assays at low testosterone levels. Lastly, the role of testosterone and other serum androgens as prognostic and predictive biomarkers in mCRPC requires more study.
APCCC 2019: Testosterone Measurement - Which Test and When?
 
#2
The Canadian consensus statement recommends achieving a serum testosterone level of less than 0.7nmol/l as there appears to be an associated clinical benefit9. Additional recommendations include regular monitoring of testosterone and PSA levels throughout the first year of ADT treatment, using validated LC-MS/MS methods for testosterone assays at low testosterone levels (<0.7 nmol/l) (0r 20 ng/dL)

In conclusion, lower testosterone levels correlate with better freedom from CRPC. Breakthrough testosterone levels above 1.7 nmol/l have higher rates of failure. Testosterone levels should be assessed periodically to ensure castrate levels (every 3- months), with confirmation of lab assays at low testosterone levels. Lastly, the role of testosterone and other serum androgens as prognostic and predictive biomarkers in mCRPC requires more study.
APCCC 2019: Testosterone Measurement - Which Test and When?
Then again, from my employer:

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