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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Potential Benefits of Sermorelin and growth hormone releasing peptides
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<blockquote data-quote="pscarb" data-source="post: 12417" data-attributes="member: 2505"><p>CJC-1295 is an experimental substance. I am not suggesting the use or abuse of these peptides, as they are not for human consumption.</p><p></p><p> In my research, I have seen/heard that the following combo is ideal. CJC 1295 NO DAC (MOD GRF 1-29) with IPAMORELIN.</p><p> Google this combo, you will find some very interesting information.</p><p> </p><p>Last but not least&#8230; there is some bad press on CJ1295.</p><p></p><p> <a href="http://www.aidsmap.com/Lipodystrophy-study-halted-after-patient-death/page/1424427/" target="_blank">http://www.aidsmap.com/Lipodystrophy-study-halted-after-patient-death/page/1424427/</a></p><p></p><p> <a href="http://www.vpxsports.com/article-detail/ghrp6-and-cj1295-peptides-linked-to-death-in-athlete" target="_blank">http://www.vpxsports.com/article-detail/ghrp6-and-cj1295-peptides-linked-to-death-in-athlete</a></p><p></p><p> <a href="http://www.triplem.com.au/sydney/sport/nrl/news/2013/9/exclusive-insider-exposes-real-danger-on-taking-peptides-like-cjc-1295/" target="_blank">http://www.triplem.com.au/sydney/sport/nrl/news/2013/9/exclusive-insider-exposes-real-danger-on-taking-peptides-like-cjc-1295/</a></p><p></p><p></p><p> Also here is an interesting document about the Synergy of L-arginine and GHRP2 stimulation.</p><p></p><p>Semorelin, CJC1295 w/o DAC, CJC1295 with DAC, CJC1296, CJC1293 and Modified (MOD) GRF 1-29 are all GHRH peptides the main differences is how quickly they degrade in the body once injected. </p><p></p><p>Now Sermorelin, GHRH(1-44) and GRF(1-29) all are basically GHRH and have a short half-life in plasma because of quick cleavage between the 2nd & 3rd amino acid. This is no worry naturally because this hormone is secreted from the hypothalamus and travels a short distance to the underlying anterior pituitary and is not really subject to enzymatic cleavage. The release from the hypothalamus and binding to somatotrophs (pituitary cells) happens quickly.</p><p></p><p>However when injected into the body it must circulate before finding its way to the pituitary and so within 3 minutes it is already being degraded.</p><p></p><p>That is why GHRH in the above forms must be dosed high to get an effect.</p><p></p><p>So if you want to inject it, it has to travel in the blood stream where it is subject to degradation. So if you inject GRF(1-29) or GHRH into a body it will degrade withing a few minutes. Sure some will bind in the pituitary but most will not. this is why Modified GRF 1-29 is a far better option as the degradation is approx 30min.......</p></blockquote><p></p>
[QUOTE="pscarb, post: 12417, member: 2505"] CJC-1295 is an experimental substance. I am not suggesting the use or abuse of these peptides, as they are not for human consumption. In my research, I have seen/heard that the following combo is ideal. CJC 1295 NO DAC (MOD GRF 1-29) with IPAMORELIN. Google this combo, you will find some very interesting information. Last but not least… there is some bad press on CJ1295. [URL]http://www.aidsmap.com/Lipodystrophy-study-halted-after-patient-death/page/1424427/[/URL] [URL]http://www.vpxsports.com/article-detail/ghrp6-and-cj1295-peptides-linked-to-death-in-athlete[/URL] [URL]http://www.triplem.com.au/sydney/sport/nrl/news/2013/9/exclusive-insider-exposes-real-danger-on-taking-peptides-like-cjc-1295/[/URL] Also here is an interesting document about the Synergy of L-arginine and GHRP2 stimulation. Semorelin, CJC1295 w/o DAC, CJC1295 with DAC, CJC1296, CJC1293 and Modified (MOD) GRF 1-29 are all GHRH peptides the main differences is how quickly they degrade in the body once injected. Now Sermorelin, GHRH(1-44) and GRF(1-29) all are basically GHRH and have a short half-life in plasma because of quick cleavage between the 2nd & 3rd amino acid. This is no worry naturally because this hormone is secreted from the hypothalamus and travels a short distance to the underlying anterior pituitary and is not really subject to enzymatic cleavage. The release from the hypothalamus and binding to somatotrophs (pituitary cells) happens quickly. However when injected into the body it must circulate before finding its way to the pituitary and so within 3 minutes it is already being degraded. That is why GHRH in the above forms must be dosed high to get an effect. So if you want to inject it, it has to travel in the blood stream where it is subject to degradation. So if you inject GRF(1-29) or GHRH into a body it will degrade withing a few minutes. Sure some will bind in the pituitary but most will not. this is why Modified GRF 1-29 is a far better option as the degradation is approx 30min....... [/QUOTE]
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Peptide Forums (GHRH, Sermorelin, etc)
General Peptide Use & Information
Potential Benefits of Sermorelin and growth hormone releasing peptides
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