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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Estradiol Boosts Libido in Men on Testosterone Therapy
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<blockquote data-quote="Nelson Vergel" data-source="post: 6388" data-attributes="member: 3"><p><strong>Estradiol in Men</strong></p><p></p><p>Estradiol is important and not a single study (I have read them all) have come up with what the highest level is before being considered to have excess estradiol. I have gone through gynecomastia data in teenagers and many do not of these kids do not have high estradiol. What they have is low testosterone to estradiol ratios (under 10 if you divide TT in ng/dL by estradiol in pg/mL). It seems that T/E ratios of over 14 tend to minimize issues related to gynecomastia and decreased fertility.</p><p></p><p>As testosterone goes up, so does estradiol. Testosterone is estradiol's prohormone for a good reason. Like testosterone, estradiol regulates sex drive and cognitive function. There are two estradiol receptors (alpha and beta) that have different functions. Depending on medications, liver issues, genetic predisposition, etc some men tend to produce T and E2 in lower T/E2 ratios than others. Low T/E2 ratios may be linked to gynecomastia, low fertility, low sex drive, etc</p><p></p><p>You will find that ExcelMale is the only forum where estradiol data is being closely followed. I am pretty obsessed with this since I believe a lot of guys are tanking their estradiol. These guys will eventually have low bone density, low sex drive, and low cognitive function as they age.</p><p></p><p>One more thing: many men are getting their estradiol measured with the regular test instead of the ultrasensitive. I did not believe there was much of a difference (the ultrasensitive E2 test is also more expensive). A few of us got our estradiol tested by both methods from the same blood sample and found out that the ultrasensitive tests E2 value were at most half of E2 measured by the regular test. This can also imply that many guys are being over treated with anastrozole based on inflated E2 values.</p><p></p><p>I am attaching a paper that discusses estradiol in men for those of you who like to read. I would suggest you do so before you attack my views.</p><p></p><p>I have written about this issue and posted it here:</p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/role-of-estradiol-estrogen-in-men-and-its-management.2309/[/URL]</p><p></p><p></p><p><a href="https://www.excelmale.com/forum/threads/1178-Why-All-Men-Should-be-Tested-with-the-Ultrasensitive-Estradiol-Test?highlight=ultrasensitive" target="_blank">Why All Men Should be Tested with the Sensitive Estradiol Test</a></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 6388, member: 3"] [B]Estradiol in Men[/B] Estradiol is important and not a single study (I have read them all) have come up with what the highest level is before being considered to have excess estradiol. I have gone through gynecomastia data in teenagers and many do not of these kids do not have high estradiol. What they have is low testosterone to estradiol ratios (under 10 if you divide TT in ng/dL by estradiol in pg/mL). It seems that T/E ratios of over 14 tend to minimize issues related to gynecomastia and decreased fertility. As testosterone goes up, so does estradiol. Testosterone is estradiol's prohormone for a good reason. Like testosterone, estradiol regulates sex drive and cognitive function. There are two estradiol receptors (alpha and beta) that have different functions. Depending on medications, liver issues, genetic predisposition, etc some men tend to produce T and E2 in lower T/E2 ratios than others. Low T/E2 ratios may be linked to gynecomastia, low fertility, low sex drive, etc You will find that ExcelMale is the only forum where estradiol data is being closely followed. I am pretty obsessed with this since I believe a lot of guys are tanking their estradiol. These guys will eventually have low bone density, low sex drive, and low cognitive function as they age. One more thing: many men are getting their estradiol measured with the regular test instead of the ultrasensitive. I did not believe there was much of a difference (the ultrasensitive E2 test is also more expensive). A few of us got our estradiol tested by both methods from the same blood sample and found out that the ultrasensitive tests E2 value were at most half of E2 measured by the regular test. This can also imply that many guys are being over treated with anastrozole based on inflated E2 values. I am attaching a paper that discusses estradiol in men for those of you who like to read. I would suggest you do so before you attack my views. I have written about this issue and posted it here: [URL unfurl="true"]https://www.excelmale.com/forum/threads/role-of-estradiol-estrogen-in-men-and-its-management.2309/[/URL] [URL='https://www.excelmale.com/forum/threads/1178-Why-All-Men-Should-be-Tested-with-the-Ultrasensitive-Estradiol-Test?highlight=ultrasensitive']Why All Men Should be Tested with the Sensitive Estradiol Test[/URL] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
High Estradiol Boosts Libido in Men on Testosterone Therapy
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