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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Heavier Men May Require Higher TRT Doses
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<blockquote data-quote="madman" data-source="post: 183141" data-attributes="member: 13851"><p>You are being over-medicated and you need to find a new doctor who specializes in trt.</p><p></p><p>Your TT levels are >52 nmol/L (>1500 ng/dL) and that is at the trough.</p><p></p><p>The dose of T you are injecting 300mg/week (150mg every 3.5 days) is not a trt dose.</p><p></p><p>Let alone your doctor is only testing your TT level/CBC/ALP (requisition you posted) and again he should be testing FT and estradiol.</p><p></p><p>FT is what matters as it is the active unbound fraction responsible for the positive effects.</p><p></p><p>Patients with Kleinfelter's syndrome would in no way need doses higher than what is commonly prescribed (100-200mg/week) in men with hypogonadism to achieve a healthy FT level which will result in relief/improvement of low-t symptoms and overall well-being.</p><p></p><p>I will agree that FT testing is poor in Canada and unfortunately, we do not have access to the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best) but if anything at least the direct analog immunoassay has been replaced with the calculated linear law-of-mass action Vermuelen (mind you it is flawed).</p><p></p><p>Most labs across Canada should at least be using the calculated Vermeulen and even then it is available online as you just need to know your TT/SHBG/Albumin levels mind you if you do not know where your Albumin sits than you can just you the mean 4.3 g/dL.</p><p></p><p>Unfortunately, your SHBG was never tested.</p><p></p><p>You can get a better idea of where your FT sits by using the newer calculated TruT which is available online for free <a href="https://tru-t.org/" target="_blank">TruT Free Testosterone Calculator by FPT</a></p><p></p><p>If you are willing to drive across the border and have your bloodwork done at a <span style="color: rgb(184, 49, 47)">Quest Diagnostics</span> location in the US which is close to the Canadian border where you reside (Alberta) then you have the option to order the most accurate assays for TT (LC/MS-MS), FT (Equilibrium Dialysis or Ultrafiltration), estradiol sensitive (LC/MS-MS) from Nelson's <a href="https://www.discountedlabs.com/" target="_blank">Discounted Labs Most Popular Blood Tests | Discounted Labs</a>.</p><p></p><p>The only way you could have the estradiol sensitive (LC/MS-MS) done in Canada would be through Dynacare in the province of Ontario as unfortunately, it is not available in any of the other provinces yet.</p><p></p><p>You need to take a step back and think this through.</p></blockquote><p></p>
[QUOTE="madman, post: 183141, member: 13851"] You are being over-medicated and you need to find a new doctor who specializes in trt. Your TT levels are >52 nmol/L (>1500 ng/dL) and that is at the trough. The dose of T you are injecting 300mg/week (150mg every 3.5 days) is not a trt dose. Let alone your doctor is only testing your TT level/CBC/ALP (requisition you posted) and again he should be testing FT and estradiol. FT is what matters as it is the active unbound fraction responsible for the positive effects. Patients with Kleinfelter's syndrome would in no way need doses higher than what is commonly prescribed (100-200mg/week) in men with hypogonadism to achieve a healthy FT level which will result in relief/improvement of low-t symptoms and overall well-being. I will agree that FT testing is poor in Canada and unfortunately, we do not have access to the most accurate assay such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best) but if anything at least the direct analog immunoassay has been replaced with the calculated linear law-of-mass action Vermuelen (mind you it is flawed). Most labs across Canada should at least be using the calculated Vermeulen and even then it is available online as you just need to know your TT/SHBG/Albumin levels mind you if you do not know where your Albumin sits than you can just you the mean 4.3 g/dL. Unfortunately, your SHBG was never tested. You can get a better idea of where your FT sits by using the newer calculated TruT which is available online for free [URL='https://tru-t.org/']TruT Free Testosterone Calculator by FPT[/URL] If you are willing to drive across the border and have your bloodwork done at a [COLOR=rgb(184, 49, 47)]Quest Diagnostics[/COLOR] location in the US which is close to the Canadian border where you reside (Alberta) then you have the option to order the most accurate assays for TT (LC/MS-MS), FT (Equilibrium Dialysis or Ultrafiltration), estradiol sensitive (LC/MS-MS) from Nelson's [URL='https://www.discountedlabs.com/']Discounted Labs Most Popular Blood Tests | Discounted Labs[/URL]. The only way you could have the estradiol sensitive (LC/MS-MS) done in Canada would be through Dynacare in the province of Ontario as unfortunately, it is not available in any of the other provinces yet. You need to take a step back and think this through. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
Heavier Men May Require Higher TRT Doses
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