HCG Monotherapy experience (just sharing)

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SMOS44

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Prior to HCG monotherapy baseline:
Total T ~350ng/dL
SHBG ~17 nmol/L
Estrodial ~25 pg/ml
Free T ~13pg/mL.

I was prescribed HCG 3x per week at 300 units each day. Results:
Total T 326ng/dl
SHBG 11 nmol/L
Estrodial ~25 pg/ml
Free T ~20pg/mL

I should note that LH/FSH were 7/2 respectively before and <1 for each on HCG... the HPTA was more or less fully disrupted.

I was on HCG for about 7 weeks in total. Within that time period, for about a month, the doctor also gave me some Tlando to experiment with taking concurrently. I did not take Tlando at the time of either blood test. I suspect that my testicles actually produce a solid amount of T and that my low SHBG causes the free T to fluctuate too much which causes my symptoms. Just a theory. HCG Monotherapy did alleviate some symptoms to a degree, but the biggest difference came during the period that I also took Tlando.


I think going forward I will get off of HCG/Tlando and try buccal troches/Natesto. I'm paranoid about brain aging which I think is associated with high peripheral HCG/LH. Also, it's clear to me that because my SHBG is low I don't need much T. When I was taking Tlando I made substantial progress in the Gym and with my Libido. This leads me to believe I was potentially supraphysiologic. I was also concerned because my LDL was high and HDL was low on the HCG Monotherapy protocol while they were always near perfect before.

During the time period when I took both HCG and Tlando I was surprised that on the first day not much happened, but after 2-3 consecutive days I could feel a marked difference. Also, there was no 'ebb and flow' noticeable that I suspected would coincide with the rise and decline of T from Tlando in the middle of the day. I don't think the body/brain responds immediately to higher T, I think there must be some signaling that accumulates over time. I also felt like the benefits lasted a bit more than a day after I stopped taking the Tlando. This is surprising because Tlando really only raises T for ~12h or so.
 
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