ExcelMale
Menu
Home
What's new
Latest activity
Forums
New posts
Search forums
What's new
New posts
Latest activity
Videos
Lab Tests
Doctor Finder
Buy Books
About Us
Men’s Health Coaching
Log in
Register
What's new
Search
Search
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Navigation
Install the app
Install
More options
Contact us
Close Menu
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Message
<blockquote data-quote="tareload" data-source="post: 243883"><p><strong>FUN WITH TT/FT Blood Work Part II </strong>(dedicated to [USER=13851]@madman[/USER] for all his efforts posting on this site and to get my steak dinner LOL):</p><p></p><p><strong>Labcorp:</strong></p><p></p><p>I have outdone myself here as I got blood drawn and had the technician order BOTH:</p><p></p><p>[URL unfurl="true"]https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences[/URL]</p><p></p><p>AND</p><p></p><p>[URL unfurl="true"]https://www.labcorp.com/tests/070195/testosterone-free-direct-with-total-testosterone-lc-ms-ms[/URL]</p><p></p><p>This allows me to get two different labs to measure TT via LCMS (with claimed CDC HoST status) plus FT by equilibrium dialysis and the direct analog enzyme immunoassay (aka direct FT test).</p><p></p><p>BEHOLD:</p><p><strong>[ATTACH=full]28607[/ATTACH]</strong></p><p><strong></strong></p><p><strong>[ATTACH=full]28608[/ATTACH]</strong></p><p></p><p>First, let's use the Esoterix lab as the standard (arbitrary) even though both Labcorp's Esoterix Lab and Burlington Lab have HoST certification:</p><p></p><p>% difference = (1081-992.6)/1081 *100 = 8.2% difference between the two CDC HoST certified labs.</p><p></p><p><em>Esoterix sounds more impressive than Burlington so it has that going for it.</em></p><p><em></em></p><p>Second, Labcorp FT by equilibrium dialysis = 22.7 ng/dl. Remember Quest FT by ED on same sample was 24.5 ng/dl (see above). So regardless of the different reference ranges both assays have very similar FT result. Labcorp's Esoterix TT by MS and Quest TT by MS are also very close (1081 vs 1103 ng/dl).</p><p></p><p>Third, what does the Labcorp direct FT test tell us. Using the <a href="https://www.excelmale.com/forum/threads/public-service-announcement-piss-poor-direct-ria-ft-measurement-help-is-on-the-way.25288/" target="_blank">handy transfer function tool I detailed in another thread</a>:</p><p></p><p>Adjusted FT (direct) = 27.6 pg/ml * 7 / 10 = 19.3 ng/dl</p><p></p><p>Quite a bit lower than either Labcorp or Quest's FT by ED but in the ball park.</p><p>% difference = (24.5-19.3)/24.5 = 21%</p><p></p><p>So to summarize, on the same blood sample roughly approximating peak blood levels 24 hours after injection for TC (of course off on the TP part):</p><p></p><ol> <li data-xf-list-type="ol">TT (Quest MS) = 1103 ng/dl</li> <li data-xf-list-type="ol">TT (Labcorp Esoterix LCMS) = 1081 ng/dl</li> <li data-xf-list-type="ol">TT (Labcorp Burlington (LCMS) = 993 ng/dl</li> <li data-xf-list-type="ol">FT (Quest ED) = 24.5 ng/dl</li> <li data-xf-list-type="ol">FT (Labcorp Esoterix ED) = 22.7 ng/dl</li> <li data-xf-list-type="ol">FT (adj direct FT EIA) = 19.3 ng/dl</li> <li data-xf-list-type="ol">cFTV (Vermeulen) ~ 27.1 ng/dl</li> <li data-xf-list-type="ol">adjusted cFTV (90% of CFTV) ~ 24.4 ng/dl</li> <li data-xf-list-type="ol">TruT ~ 38.9 ng/dl </li> </ol><p>A few of takeaways for me:</p><ul> <li data-xf-list-type="ul">Both Labcorp and Quest agree pretty well on measured FT via ED even through reference ranges are quite different as we discussed before).</li> <li data-xf-list-type="ul">The adjusted direct FT still gets you in the ballpark although the low price of the FT by ED using [USER=3]@Nelson Vergel[/USER]'s Discounted Labs make it stupid easy to get FT by ED with very low cost.</li> <li data-xf-list-type="ul">Interlab variability with the two Labcorp HoST sites was ~8% for my blood sample.</li> <li data-xf-list-type="ul">TruT calculator as it currently exists on the website SUCKS unless Labcorp and Quest are both measuring FT wrong. Neither Quest nor Labcorp line up with the training set TruT claims matches their calculated values. If Labcorp and Quest are both full of sh*t then why are we telling guys to keep ordering these tests LOL?</li> </ul><p></p><p>RIP TruT (CFTZ) v1.0:</p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/reference-intervals-for-free-testosterone-in-adult-men-measured-using-a-standardized-equilibrium-dialysis-procedure.26279/post-237074[/URL]</p><p></p><p>See this thread for more information than you probably want. Now you don't have to post the question about which free T calculator to use until Madman posts up the next Phase 2 validation results for TruT.</p><p></p><p>Now let's see how many likes these posts get. Come on I need the dopamine hits. Congratulations if you made it all the way through both posts.</p></blockquote><p></p>
[QUOTE="tareload, post: 243883"] [B]FUN WITH TT/FT Blood Work Part II [/B](dedicated to [USER=13851]@madman[/USER] for all his efforts posting on this site and to get my steak dinner LOL): [B]Labcorp:[/B] I have outdone myself here as I got blood drawn and had the technician order BOTH: [URL unfurl="true"]https://www.labcorp.com/tests/500726/testosterone-free-mass-spectrometry-equilibrium-dialysis-endocrine-sciences[/URL] AND [URL unfurl="true"]https://www.labcorp.com/tests/070195/testosterone-free-direct-with-total-testosterone-lc-ms-ms[/URL] This allows me to get two different labs to measure TT via LCMS (with claimed CDC HoST status) plus FT by equilibrium dialysis and the direct analog enzyme immunoassay (aka direct FT test). BEHOLD: [B][ATTACH type="full" alt="1674489200574.png"]28607[/ATTACH] [ATTACH type="full" alt="1674489290709.png"]28608[/ATTACH][/B] First, let's use the Esoterix lab as the standard (arbitrary) even though both Labcorp's Esoterix Lab and Burlington Lab have HoST certification: % difference = (1081-992.6)/1081 *100 = 8.2% difference between the two CDC HoST certified labs. [I]Esoterix sounds more impressive than Burlington so it has that going for it. [/I] Second, Labcorp FT by equilibrium dialysis = 22.7 ng/dl. Remember Quest FT by ED on same sample was 24.5 ng/dl (see above). So regardless of the different reference ranges both assays have very similar FT result. Labcorp's Esoterix TT by MS and Quest TT by MS are also very close (1081 vs 1103 ng/dl). Third, what does the Labcorp direct FT test tell us. Using the [URL='https://www.excelmale.com/forum/threads/public-service-announcement-piss-poor-direct-ria-ft-measurement-help-is-on-the-way.25288/']handy transfer function tool I detailed in another thread[/URL]: Adjusted FT (direct) = 27.6 pg/ml * 7 / 10 = 19.3 ng/dl Quite a bit lower than either Labcorp or Quest's FT by ED but in the ball park. % difference = (24.5-19.3)/24.5 = 21% So to summarize, on the same blood sample roughly approximating peak blood levels 24 hours after injection for TC (of course off on the TP part): [LIST=1] [*]TT (Quest MS) = 1103 ng/dl [*]TT (Labcorp Esoterix LCMS) = 1081 ng/dl [*]TT (Labcorp Burlington (LCMS) = 993 ng/dl [*]FT (Quest ED) = 24.5 ng/dl [*]FT (Labcorp Esoterix ED) = 22.7 ng/dl [*]FT (adj direct FT EIA) = 19.3 ng/dl [*]cFTV (Vermeulen) ~ 27.1 ng/dl [*]adjusted cFTV (90% of CFTV) ~ 24.4 ng/dl [*]TruT ~ 38.9 ng/dl [/LIST] A few of takeaways for me: [LIST] [*]Both Labcorp and Quest agree pretty well on measured FT via ED even through reference ranges are quite different as we discussed before). [*]The adjusted direct FT still gets you in the ballpark although the low price of the FT by ED using [USER=3]@Nelson Vergel[/USER]'s Discounted Labs make it stupid easy to get FT by ED with very low cost. [*]Interlab variability with the two Labcorp HoST sites was ~8% for my blood sample. [*]TruT calculator as it currently exists on the website SUCKS unless Labcorp and Quest are both measuring FT wrong. Neither Quest nor Labcorp line up with the training set TruT claims matches their calculated values. If Labcorp and Quest are both full of sh*t then why are we telling guys to keep ordering these tests LOL? [/LIST] RIP TruT (CFTZ) v1.0: [URL unfurl="true"]https://www.excelmale.com/forum/threads/reference-intervals-for-free-testosterone-in-adult-men-measured-using-a-standardized-equilibrium-dialysis-procedure.26279/post-237074[/URL] See this thread for more information than you probably want. Now you don't have to post the question about which free T calculator to use until Madman posts up the next Phase 2 validation results for TruT. Now let's see how many likes these posts get. Come on I need the dopamine hits. Congratulations if you made it all the way through both posts. [/QUOTE]
Insert quotes…
Verification
Post reply
Share this page
Facebook
Twitter
Reddit
Pinterest
Tumblr
WhatsApp
Email
Share
Link
Sponsors
Forums
Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
Calculate Free Testosterone with TruT by FPT
This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register.
By continuing to use this site, you are consenting to our use of cookies.
Accept
Learn more…
Top