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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
A SERM (fispemifene) increases testosterone but not sex drive
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<blockquote data-quote="Dr Justin Saya MD" data-source="post: 35788" data-attributes="member: 12687"><p>Everyone should note they state "While we did see statistically meaningful changes in testosterone levels into the low normal ranges with fispemifene, the compound's ability to increase those levels sufficiently to demonstrate clinical benefit is limited, and may be an issue with the entire SERM class"...</p><p></p><p>When have testosterone levels in the "low normal ranges" EVER resulted in "clinical benefit"? Even frank TRT with levels in the "low normal" ranges typically fails to produce "clinical benefit". </p><p></p><p>Crazy with billions of dollars at stake in this market that they have such flaws in their studies and now are scrapping the entire development of the drug...they need more knowledgeable/experienced folks designing/running the studies (likely same problem with Repros).</p></blockquote><p></p>
[QUOTE="Dr Justin Saya MD, post: 35788, member: 12687"] Everyone should note they state "While we did see statistically meaningful changes in testosterone levels into the low normal ranges with fispemifene, the compound's ability to increase those levels sufficiently to demonstrate clinical benefit is limited, and may be an issue with the entire SERM class"... When have testosterone levels in the "low normal ranges" EVER resulted in "clinical benefit"? Even frank TRT with levels in the "low normal" ranges typically fails to produce "clinical benefit". Crazy with billions of dollars at stake in this market that they have such flaws in their studies and now are scrapping the entire development of the drug...they need more knowledgeable/experienced folks designing/running the studies (likely same problem with Repros). [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone and Men's Health Articles
A SERM (fispemifene) increases testosterone but not sex drive
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