Hcg not increasing testes

trt4me · Oct 14, 2016

Has anyone seen (including saya) Hcg not increase teste size and or stop working?
Seems to be the case with me now, they shrunk again and pull up and like clock work libido is down. I am a patient of defy so I should cal them.
Currently taking 300iu eod.

CPTWilly · Oct 14, 2016

I just started on HCG. My doc started low and will adjust up--he's trying to avoid a spike in E2.

Anyway, how long did it take for you to see improvement?

Vince · Oct 14, 2016

HPTA suppressed and HCG it will help to gain back some of the testicular size but for many men the testes never reach the size pre TRT.

I like increased penis sensitivity which makes sex great.
I use 500iu twice a week.

trt4me · Oct 14, 2016

Guess what I'm asking is if anyone has seen Hcg stop working where it once was for teste size.
Over the last month or 2 they have struck again while still using Hcg.

Loki · Oct 14, 2016

For me I have extreme testes volatility... Some days they are full and hang low, last night I could barely find them... Not sure if it is related to body temp, HCG or some other factor... I am trying 400 units 3 times per week... Doesn't seem to be changing anything... I will say this, when I stopped TRT and started clomid they blew up to the size of eggs!!!! I just felt terrible, but has some huge nuts

....

Vince Carter · Oct 14, 2016

Are you pulling Estrogen at these times, what was your last E2 sensitive reading? I wouldn't go right to HCG itself at this point. And its just IMHO that 300iu EOD is more than is necessary, may be stimulating E conversion in the testes which is rather tough to control even with an AI.

trt4me · Oct 14, 2016

I haven't got me e2 checked recently but Hcg has never raised it much but I should get it checked anyway.

CoastWatcher · Oct 14, 2016

I'd run total and free testosterone, and estradiol/sensitive. Without backup we're all just guessing.

ERO · Oct 14, 2016

HCG has never done anything for my testes in terms of size, regardless of dosage or frequency of injections. Nor has it ever done anything for my libido. Everybody responds differently.

trt4me · Oct 14, 2016

I will most likely run labs but I have never heard of e2 affecting teste size.

CPTWilly · Oct 14, 2016

Any chance you got a bad batch of hcg? Or that it has degraded?

Vince · Oct 14, 2016

CPTWilly said:
Any chance you got a bad batch of hcg? Or that it has degraded?

I was wondering the same thing.

ERO · Oct 14, 2016

trt4me said:
I will most likely run labs but I have never heard of e2 affecting teste size.

The HCG is what may, or may not, be affecting testes size. You can get a pregnancy test at the Dollar Store and test your HCG if you want. If you are "pregnant" then the HCG is good. It cannot tell you the strength of the HCG, though.

Nelson Vergel · Oct 15, 2016

I believe some men may need higher doses than 300 IU, as seen in this study.

Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression

This study shows that HCG can keep intratesticular (inside the testes) testosterone - ITT normal even when they are exposed to testosterone injections. An HCG dose of 500 IU every other day increased ITT to levels higher than baseline. All other doses failed to achieve normalization of baseline ITT. ITT is crucial for Leydig cells to work properly so that they do not atrophy (lose volume due to inactivity)

http://www.ncbi.nlm.nih.gov/m/pubmed/15713727/

trt4me · Oct 15, 2016

Thanks for hat Nelson. I have a feeling I need more but waiting on a callback from defy to discuss. I don't think it's a bad batch as this started at the end of one bottle and I started a new one from a new pharmacy and still the issue exists.

Hcg not increasing testes

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