Are guys that do well on low dose clomid unicorns...or do they really exist?

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Thanks for the quick feedback. Yah, my FSH & LH are/were zero before I took the hcg. I’m using hcg to counteract the atrophy I was experiencing which was very painful. It solved that problem but then the other stuff all kicked in. Maybe changing protocols wit T is an answer. I’m actually getting a Nebido shot this Friday so will be stopping gels and see how that goes. I’d herd that enclomiphine would provide the same physical effects as hcg. If I’m feeling emotional and have these sensitivities should I just ignore them or is that an E issue. Really appreciate feedback and thoughts
 
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Speed

Member
Nebido is not a great option.....hard to adjust the dose, but better than nothing...
Hcg is also suppresive for lh/fsh, so Probaby still too low on T... HCG is not LH, it mimics lh but on LH test, you can not see hcg as lh.

Forget about clomid/enclomiphene, terrible drugs... Your numbers can look great on it, but most prople on it feel terrible. And also you are on T, using clomid/enclomiphene alongside is nonsense because T is suprresive for lh/fsh and then you are trying to bring lh up with clomid while still using T, which is not possible. You have to find a better provider, or learn how HPTA works, so you can understand when and why you can use different drugs. Don't lose precious time with bad protocols or providers. Have a nice day
 

DCameronMauch

New Member
Something shifted in my body a while ago, and suddenly my T was < 50, sometimes < 20. Did TRT for a while, but an endo suggested Clomid. Been taking 1/2 a 50mg pill nightly for several years now. My T stays stable around 750. So it sure as hell works for me. The only problem is that the generic is gone, and even the brand name is difficult to get and super expensive.
 

Nik

Member
Something shifted in my body a while ago, and suddenly my T was < 50, sometimes < 20. Did TRT for a while, but an endo suggested Clomid. Been taking 1/2 a 50mg pill nightly for several years now. My T stays stable around 750. So it sure as hell works for me. The only problem is that the generic is gone, and even the brand name is difficult to get and super expensive.

Something shifted in my body a while ago, and suddenly my T was < 50, sometimes < 20. Did TRT for a while, but an endo suggested Clomid. Been taking 1/2 a 50mg pill nightly for several years now. My T stays stable around 750. So it sure as hell works for me. The only problem is that the generic is gone, and even the brand name is difficult to get and super expensive.
How long were you on trt, any visual effects with clomiphene?
 

jc2c

Member
View attachment 1757

They actually EXIST!!!

There are certainly some challenges in treating with low dose clomid, specifically in dealing with the varying effect (estrogen antagonist/agonist) of the two isomers enclomiphene and zuclomiphene. However, as I (and Dr Crisler) have said many times...I DO ACHIEVE SUCCESS in a fair number of guys with both a good objective AND subjective (symptomatic) response. This is one of my patients. Now there are certainly many guys that do NOT respond well to clomid for various reasons (wrong dosing, mismanagement, poor estrogen control, high SHBG, lack of response from HPTA, or just simply not tolerating the medication), but there are also many that have a good and even great response.

Admittedly, the online and forum tone is overwhelmingly negative regarding clomid...as for some reason the guys that actually do well on clomid (you know who you are...LOL) are not as vocal as the guys who've had a negative experience. I've seen the quote many times in one form or another as a matter of fact statement: "clomid will get your T levels up, but you won't feel it...or you won't feel better". Indeed, there are guys that feel good and even great on clomid, from my estimation anywhere from 30-50% of the guys (especially under 40yo) that I treat. It does, however, take PATIENCE and I think this is where some guys give up too quicky, possibly partly due to the negative bias that they had already formed from their "expectations" of clomid not working for anyone. For a younger guy (or even older...my oldest guy on clomid is 58yo and has had a GREAT response...he doesn't want to come off!) that can or wants to stimulate his endogenous testosterone production, maintain OPTIMAL fertility, and buy himself precious years of natural production before having to rely on TRT - clomid can be a perfect treatment for these guys!

After all, if it fails then the TRT option is always there as a backup plan.
I felt great on Clomid for 5 years then it just stopped working. Why does that happen? I tried switching to enclomiphene but that didn't work and ultimately had to go on TRT. I heard Dr. Mohit Khera say this happens with Clomid on Dr. Attia's podcast but he didn't explain why.
 

CKO

Active Member
Enclomiphene makes your balls huge. It feels great. Yes you develop larger muscles at The top end of the lab scales versus the lower end. But in clomiphene taken daily messes with your estrogen receptors and eventually makes you feel like crap.
 
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