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I’m just curious: is it the high blood serum dht concentrations, or is it the higher free t from scrotal cream that contributes to hairloss, or is it a combination. A doctor on a particular Facebook group suggested that dht is more intracrine/paracrine, and so serum dht is essentially...

I’m surprised the scrotal creams didn’t work for you. They are also short half life t.

I’ve tried eod shots IM. On 150mg cypionate every week. Low dht. Erections and libido sucked lol

Eli have you ever tried another ester besides cypionate? Did you ever test your dht on cypionate? Mine runs low on cypionate, and I keep seeing low shbg guys being poor converters. I have the exact same issues as you and have found that the only form of test that works is the scrotal cream...

also, can I ask why you dropped scrotal cream if it was working so well for you? Thanks

Please let us know if your dht levels change with a different ester.

What is your dht reading on injections??do u use cypionate or enanthate??

I am. Shbg 16-20 without trt. I have never tried once a week, but dailies and eod on cypionate didn’t work for me (my dht was below reference range). I started out with 100mg weekly and went all the way to 150mg weekly and dht never went within range. My problem was dht conversion with cypionate...

You can incorporate more plant based protein and less meat consumption.

I’ve seen this too where guys do better with less frequent injections, like once a week. I guess because it’s so difficult to nail the correct t to e ratio that by injecting a larger dose once a week estrogen eventually settles into the sweet spot as the week goes on.

I too have low shbg, and I don’t have diabetes or metabolic syndrome currently;however, I did a 23 and me test, and I have the genes for increased likelihood of getting diabetes( I am 75 percent more likely to get it than average person ).

I wouldn’t start eating a bunch of eggs. Everything in moderation. Too much protein is bad for the kidneys (and overall health), and your cholesterol will spike.

What is your dose of sirolimus if you don’t mind me asking?

I have to be honest here and say that the doctors at defy kinda suck. You absolutely need some kind of serm to come off trt. I’ve done it twice now, and both times I could not have done it without a serm. Low t is literal hell on earth. Using a serm will lighten the blow, and you can continue...

These are my thoughts as well. I def notice an arimidex like effect when taking Enclomiphene at higher doses

I just take metformin, some senolytics like quercitn/fisetin, nmn. I would like to try rapa if I can get a good source.

Where do you get your rapamycin??? That is the question. Can we get it through defy?

I just did mushrooms the other day. I wouldn’t I was any less depressed though. It was more like an out of body experience. Then it wore off and I was in the same shitty world. Lol

I’ve read that danazol (and possibly dht) lengthens telomeres. Rapamycin is too risky imo. With all of these longevity drugs inhibiting mtor, you’re really sacrificing quality of life for maybe a few added disease free years of lifespan if taken regularly and for a long time. Rapamycin, like...

And that’s the other thing. The mind and body work in harmony. True low t is pretty rare. Ask your primary care physician.

I totally get what you’re saying. Maybe the issue I have is trusting my friends over some random trt clinic doctors who will always tell you it’s good for you because they’re selling it and thats how they make their money.I still do not think it’s risk free and there aren’t any long term studies...

I can verify these are the exact numbers I got when doing 2x vs 1x

I also have low shbg and it seems scrotal cream was the only method that worked for me. I did eod with cypionate from 100-150 per week with no improvement in libido or erectile function. In fact it gave me ED, which I had never had in my life until I began the shots. That’s when I looked into...

Why is the medical community still stuck on it causing cancer? I for the life of me don’t understand and it’s not like they don’t keep up with the literature. One of my buddies graduated from top 10 medical school and insists i will pay the price later on. And when I mentioned studies to him, he...

Okay guys. I know I’ve been a pita on these forums and probably Nelson will fire me soon. I got my labs back after being off Enclomiphene. My lh is barely alive at 1.8. I have yet to get t levels back but I’m assuming they’re low because I feel low t symptoms. This is after a few cycles of...

I wish my insurance covered it. That’s the only catch.

You know, trt has been so difficult for me. It all started when I found out I was a poor converter to dht on cypionate injections. (I had below reference range dht, and even on 150mg cypionate per week, my dht was below the reference range. My natural levels of dht are right in the middle of the...

Yes I did. Everything was normal. Tsh was always between 1 and 2 before starting therapy. Never experienced hypo symptoms in my life. When I was placed on synthroid by this doctor my tsh was above 3 because of the high levels of test he had me on (and this was the first time I felt hypo but...

Thanks but I think you’re missing the point. The doctor who prescribed me t wound up overdosing me which screwed up my thyroid. Instead of lowering my t dose he prescribed me synthroid (which he also overdosed me on according to my labs). My tsh is currently a little high from my normative...

Yea I think it will shorten the lifespan of users but to what degree we may never know. Seems like a lot of these trt clinics claim to be helping you but are actually hurting you in the long run.still if the pros outweigh the cons then it may not have been a bad decision for you

What is your dose read a lot?do you regret starting trt?