Johann - based on her age, your wife is approaching (sooner or later) menopause, with the average age range typically 45-55 years old. However, menopause is not an event, but more of a GRADUAL process whereby the ovaries shut down their hormone production (this process can occur over the span of weeks, sometimes months, or even years).
Symptoms vary depending on the specific hormone deficiencies, by include:
- night sweats, hot flashes, vaginal dryness/painful intercourse, dry skin, dry/achy joints (estrogen)
- lower concentration, "foggy" or scatter-brained" (as women often quote), poor sleep, anxiety (progesterone, also some interplay with other hormones)
- low libido, poor arousal/sexual satisfaction, low energy, poor recovery, loss of muscle mass or difficulty maintaining/gaining muscle mass, increase in fat, low mood/depression, lack of motivation/ambition, etc (testosterone)
Hope this helps. Symptoms help guide treatment equally if not more so than the lab results.