When evaluating T, we look at the total T, as well as the free T. But when we look at estradiol, there seems to be only one number. Does the estradiol test measure free estradiol, or total?
It would seem to me that if estradiol is bound to SHBG, then it would be of little consequence, and less need to lower it. But if you have low SHBG, more of the estradiol would be active, and therefore it may be affecting you more.
i have read here about the uncertainties regarding lowering estradiol, and am trying to understand it better.
Before TRT my estradiol was about 13. Now it is 39, at the top of the reference range. Not terrible from what I understand. However, in an effort to increase my sex drive, my doc has prescribed an AI. He said since my free T is high, therefore my SHBG is low.
With low SHBG, would estradiol have more effect on a guy?
It would seem to me that if estradiol is bound to SHBG, then it would be of little consequence, and less need to lower it. But if you have low SHBG, more of the estradiol would be active, and therefore it may be affecting you more.
i have read here about the uncertainties regarding lowering estradiol, and am trying to understand it better.
Before TRT my estradiol was about 13. Now it is 39, at the top of the reference range. Not terrible from what I understand. However, in an effort to increase my sex drive, my doc has prescribed an AI. He said since my free T is high, therefore my SHBG is low.
With low SHBG, would estradiol have more effect on a guy?