Permanent crash of estrogen?

[Zibernet]

Any other symptoms besides that?

Have you tried exogenous E2, on TRT or off it?
Or what other things have you tried? Maybe HCG or anything more exotic?

And what do your blood tests say?

That's already a lot of symptoms.

HCG never improved things, Clomid made things worse.

Just ordered an estradiol cream, never tried exogenous e2 before.

Blood test shows mid range e2.

 

[zancek0]

That's already a lot of symptoms.

HCG never improved things, Clomid made things worse.

Just ordered an estradiol cream, never tried exogenous e2 before.

Blood test shows mid range e2.

Yeah, these are brutal symptoms. I ask if there are other symptoms (like joint symptoms, sexual symptoms, fatigue, infections, hairloss etc) because as of now I've talked to a dozen of AI crashers and I'm trying to find a pattern. As of now it's apparent reversible AI crash cases shouldn't be equated with irreversible AI crashes. But even among each category there are differences: low genital sensation and orgasm vs high; joint pain vs lack of pain; 0 cognitive symptoms and significant symptoms etc.

Did clomid feel as if it increased low e2 symptoms or induced some new ones?
There is one aromasin case that recovered with HCG but used some other stuff alongside it. How did you feel on HCG?

Would you be willing to share any kind of tests you've done?
I don't think serum levels are relevant in isolation but with irreversible AI crashes low e2 levels with normal tt do tell us something.

 

[Pnw0031]

Most definitely. It personally helped me figure out some of my issues, though dealing with them’s another story depending on what’s up with that. Thyroid is a rate limiter for how well you can do on TRT it would seem, cortisol being a limiter on that further down the chain.

Older thread but I just recently found out I have hypothyroidism. Can only wonder if my trt woes are due to it!

 

[swolg8r]

That's already a lot of symptoms.

HCG never improved things, Clomid made things worse.

Just ordered an estradiol cream, never tried exogenous e2 before.

Blood test shows mid range e2.

A big factor I see on bloodwork for a lot of us who crashed with Aromasin is that despite injecting anywhere from high trt to supra-physiologic dosages of testosterone, estrogen doesn’t really budge. For instance, off trt my test levels are 749ng/dL but my estradiol sensitive is 25pg/mL. Then when I go on testosterone injections, despite doubling or tripling level of testosterone, my estradiol level may go up a couple points to 29-30pg/mL.

 

[swolg8r]

Older thread but I just recently found out I have hypothyroidism. Can only wonder if my trt woes are due to it!

Let us know if you get any better after taking thyroid medicine!

 

[Systemlord]

Older thread but I just recently found out I have hypothyroidism.

Thyroid hormones help the liver metabolism of testosterone. People with hypothyroidism don’t metabolize testosterone very well.