Nandrolone, joint pain and tendon healing

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Nandrolone Decanoate Improves Joint Pain in Men Within 8 Weeks: A Novel Prospective Pilot Study
Presentation at the Androgen Society Meeting on March 21, 2019 in New Orleans.
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  • Nandrolone is no longer available commercially. It is only available at compounding pharmacies since being discontinued by Watson Laboratories in 2007. It is available by prescription (200 mg/ml vials) from compounding pharmacies like EmpowerPharmacy.com
  • Nandrolone is a low-cost anabolic hormone used by HIV patients to combat wasting syndrome. It is also prescribed for several off label uses in other settings
  • An article discussing the impact its discontinuance had on HIV patients and where to find compounded options: The End of Nandrolone
  • HIV patients today rely on compounding pharmacies to source nandrolone. Usually, nandrolone is prescribed along with testosterone and other ancillaries (testosterone, HCG, AI, PDE-5, Tri-Mix)
  • There is a new opportunity in the urology/andrology field due to a growing movement within 'men's health' focused urologists towards the use of anabolic hormones to augment testosterone therapy (improve metabolic health, pain management, improve body composition, reverse age-related sarcopenia, etc). There is an increasing volume of studies being done on these effects and the doctors have been getting more progressive with prescribing nandrolone (and oxandrolone).
  • Some clinics within the "Age-Management/HRT" field prescribe nandrolone for the above reasons. It has been long used in the HRT setting to improve life quality and reverse the physical effects of aging.
  • It has been used off label in orthopedic and sports medicine settings for at least 12 years, used by more progressive orthopedic surgeons to accelerate post-surgical recovery
  • There are doctors who are aware of nandrolone's benefits and want to prescribe it but are hesitant due to the assumption they will be stigmatized by regulating agencies as a result of the heavy media coverage around hormone abuse in athletes. Recently much of the stigma appears to be residing and more doctors are comfortable prescribing nandrolone. The urologists I have encountered who are producing this research appear to be unaware or immune to any stigma around nandrolone
 
Nandrolone decanoate relieves joint pain in hypogonadal men: a novel prospective pilot study and review of the literature

For decades, testosterone has been the sole instrument
in the andrologist’s arsenal for the ongoing treatment
and management of male hypogonadism. However, with
increased interest and emerging research, there now exist
more options than ever to help combat the sequelae of this
devastating clinical condition. Nandrolone is a particularly
compelling medication that has significant beneficial effects
on joint pain in hypogonadal men, reducing their reliance
on chronic pain medication and reducing pain scores in
responding men by more than half. Although further studies
are required to replicate and characterize these findings on a
larger scale, they suggest a novel indication for a fascinating
drug that appears to hold great promise for future clinical
use. It is increasingly apparent that the field of modern
andrology is evolving rapidly with ever-expanding options
to assist our patients in novel and exciting ways.

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