How to control E2 Effectively?

[LowT2014]

Hi there

Been on TRT for 8 weeks now, my 2nd shot was Reandron 1000 (4ml T-Undecanoate) was last tuesday, after my first shot very next week I had my libido back along with strong nocturnal errections it continued to be this way until 4th or 5th week.

After 4th or 5th week my libido just vanished and no nocturnal errections at all just like pre TRT. I thought maybe 2nd shot may fix it but this is my 2nd week after 2nd shot and still no sign of libido improving and nocturnal errections?

Muscle strength is somewhat similar but little less than the first 4 weeks of treatment, muscles are fuller though. I still don't have the blooddwork yet as I am due for whole heap of Blood work in 3 weeks.


What causes sudden ED and libido drop while on TRT? so far everything point to elevated E2, so I began researching how to control it and fine tune it as every individual is different.


Read about DIM and AI, I really like DIM after reading it while AI does what it does it also have side effects. My question is once I get a lab what's the best way to handle E2 AI or DIM? or combination?


If I ever go with AI I will go with the lowest dose and see how it goes and stop once I see some improvements, any expereince you guys have with taking DIM?

Cheers

P.S Mods: My formatting of paragraphs not showing up after I post for some reason using windows 7.

 

[hondadude]

I seem to be experiencing the same issue. My first two shots my libido and erections were great, but now I how hardly no libido or erections. I know my estradiol went up, so I wonder if that's the issue and what to do about it.

 

[LowT2014]

To be honest its our doctors job to know what actually happens to the body when you introduce exogenous T, obviously all they do is reactive approach and not proactive, T to E2 conversion kills most of the benefits of TRT in my opinion. I have to tell my Endocrinologist about what killed my libido and nocturnal errections to be honest I felt so new and different for 4 weeks in terms of ED and monring stuff its not even funny.

and all of the sudden it just vanished now AI comes with side effects and I read good things about DIM but don't know anyone using it to control E2 and have blood work to tell us the story...

I much prefer DIM over AI if it works...

Cheers

 

[hondadude]

Well I don't even know what DIM or AI stands for. I'm new to all of this. I would just like my libido like it was the first couple of shots. Does HCG fix this?

 

[LowT2014]

Well I don't even know what DIM or AI stands for. I'm new to all of this. I would just like my libido like it was the first couple of shots. Does HCG fix this?

DIM,

http://www.dimfaq.com/site/articles.htm

AI is just aromatase inhibitor, a drug that;

Aromatase inhibitors work by inhibiting the action of the enzyme aromatase, which converts androgens into estrogens by a process called aromatization. Direct from wiki

http://en.wikipedia.org/wiki/Aromatase_inhibitor#Mechanism_of_Action

Cheers
P.S there are lot of trials underway for DIM.

 

[LowT2014]

HCG will cause more E2 conversion and you will be needing AI if you run HCG anyway, HCG is analog to LH, which act on gonads cell(Leydig) to make Testosterone also E2 conversion takes place in gonads with aromatase and when with negative feedback reaches pituitary via circulatory system pituitary senses E2 Via receptors and it stops further release of LH which then stops Testosterone production at the gonads.

Drugs like Clomiphene citrate etc work on the negative feedback and block it temporary thus increase the production of T at the gonadal level.

DIM works by better converting E2 to more digestible lesser estrogen so liver can easily get rid off it.

 

[hondadude]

Thank you for the explanation. I get confused of what does what. I have another appointment on Friday which will include blood work to test all the levels. So I will bring it up to the doctor and see what he says.

 

[Gene Devine]

Read this: https://www.excelmale.com/forum/sho...agement-What-you-should-know-–-By-Gene-Devine