estradiol

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  1. R

    Raise Testosterone with Anastrozole

    Is it possible to increase testosterone level with only Anastrozole? If a person is not on TRT.
  2. S

    Once anastrozole reaches stead state, does E2 stay relatively constant all else equal?

    Assuming one is on anastrozole for a a few weeks, would the E2 levels stay relatively constantly all else equal or does it continue to drive E2 down over time? Basically what I'm asking is how long does one need to be on anastrozole to know if they are on the right dose?
  3. N

    How to raise estridol when HCG won't do it.

    Hi. I have been on testosterone therapy since September 2019.during this time I have gone from injections to cream back to injections as nothing seems to get my estridol up... constantly fatigued suffering brain fog no libido and very dry skin. I current protocol is testosterone E at 200mg a...
  4. A

    Estrogen cream add or not?

    Someone mentioned on my last post add estrogen cream if I’m still having problems Ordered some on amazon How should I go about just rub a dose a day until I feel better and then drop it?
  5. J

    Commence TRT before/after Gyno Surgery?

    Hey Guys! I had gyno 10 years ago due to shady nutritional supplements. I'm having the surgery February 2021. As I understand, one of the main risk factors of the surgery is permanent loss of sensation/sensitivity of the nipples and chest area. Nipple sensitivity is one of the primary...
  6. T

    Those taking AI, what is your dose? Is there such a thing as anastrozole resistance?

    I've been taking testosterone cypionate for 4 weeks. 40mg EOD, along with 1.5mg anastrozole weekly. I was afraid that with this anastrozole dose I might be driving my estradiol down too low, but recently I measured it at 81 pg/ml. Maybe this is due to the testosterone dosage being way too...
  7. T

    Feeling emotional - Estradiol at 81pg/ml with 1.5mg anastrozole per week

    I was feeling borderline tearful again yesterday and decided to test some markers, prolactin, thyroid, estradiol and cortisol. Cortisol came back slightly below medium, FT4 on the low end, FT3 right in the middle. Prolactin was fine at 3.9 ug/l. Even kinda low. Estradiol on the other hand...
  8. Z

    Cream question

    So I posted a couple days ago about cream issues. Basically I use to do injections felt good but switched over to the cream because I heard it was the cats meow. Well early on it was great, my libido was sky high. And well actually that’s about it. Everything else felt normal. Fast foward 1 year...
  9. Z

    Cream levels super low

    So I got my labs done becuaase I was feeling very tired and fatigued. Felt just like not good at all- basically how I felt pre test. Anyways my protocol is 2 clicks twice (200mg) a day once in the morning once at night. I did my 2 clicks in the morning and got my labs done 26 hrs later (no dose...
  10. S

    Does variation in peak/trough equate to libido?

    I have been on TRT for about three years. In January I switched to daily injections in an effort to control hematocrit, acne and sleep issues. I began at 20 mg per day and have slowly decreased my dose down to what is now 14 mg per day under the theory that the lowest possible dose is best. I...
  11. T

    Sleep apnea - events per hour higher on days without AI

    Has anybody noticed this? In general I'm seeing 0.8 - 1.3 events per hour (with CPAP) and then on the third night after no AI it reliably creeps up to 2.2 - 2.4.
  12. K

    Adding hcg, can someone explain e2 conversion?

    So I’ve ordered some hcg among other things (doc won’t rx) in preparation of ceasing trt. I’m going to give it one more shot with the addition of hcg first. Can’t hurt as waking my nuts is gonna be necessary either way. im gonna start at 500mg twice a week when I do my test injections but I’ve...
  13. A

    How bad is this T:E ratio?

    So I inject 100mg weekly and I’m about to split my dose but until then I got my bloods back and e2 was high. I’m curious about how off this ratio is though? 2 days after injection T is 1066. 4 days post injection T is 865 and E2 ultrasensitive is 59pg/ml. I’m waiting on trough results.
  14. A

    Anybody have blood work from before and after splitting dose?

    I’m gonna be splitting my dose of 100mg to 50mg e3.5 days because of high sensitive e2 (865 T 59E2). I was wondering what anyone’s experience is before and after splitting
  15. A

    High e2 on 100mg

    I take 100mg once a week just got my sensitive e2 back 4 days after my shot and it was 59 range is less than 29. My Test level hasn’t come back yet but I’m freaking out because it explains why I’ve been breaking out. I could only imagine what my e2 is at the day after my shot. Should I split my...
  16. G

    How do I calculate “free estradiol”?

    Do I need to just purchase the lab? If there is one? I feel good but I’m trying to determine where I fall within these ranges. My SHBG is 15.6 My Estradiol Sensitive is 16.5 Thanks Gents!
  17. N

    Lowish estradiol and over weight

    I recently had some blood work done and my ultrasensitive e came back at 19. I'm at least 50lbs over weight. Shouldn't my estradiol be higher? Tt 413 Ft 57.9 pg/ml Shbg 34
  18. C

    Brain estrogen creation 'critical to maintain full sexual activity or desire in males'

    A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...
  19. E

    Complete apathy/depression from too high E2?

    I started TRT 5 weeks ago on 24mg/day subcutaneous injections of Test C (168mg/week). My doc put me on a relatively high dose because my SHBG is very high (maybe 2-3 standard deviations out of range), so much so that despite having naturally high TT levels, my FT was in the dumpster all the way...
  20. R

    Lump Under nipple but low estradiol.

    I’ve been on TRT for about a year now and taking test 200 cyp @ .4 2x a week along with HCG @ 500 iu’s 2x a week. Started taking anastrazole .125 2x a week about 8 weeks in because a lump develop under nipple. Took tamoxifen, started anastrazole and it cleared up. Fast forward approx 6-8 months...
  21. R

    Therapy change

    I've included my labs. At the time I was on .32 ml (200mg/ml) twice a week in addition to .4 ml HCG (12000 IU) 3 times a week. I was also taking 300mg DIM every day with a vitamin D supplement. I was only taking the HCG because my wife and I were trying to conceive but we have been successful...
  22. J

    I Have a prolactinoma

    I recently had an mri because of an elevated prolactin level on blood work. There is a small mass on my pituitary gland. Im bringing this up on this forum because over the last few years there has been a backlash against ai's. There actually is some research showing elevated estrogen causing...
  23. B

    When is the best time to get blood test checked?

    When is the is the best time to get your blood tested to check where TRT has your levels? Should one consider their own peaks and troughs? Currently on 2x "100mg Test C" & 2x "500IU HCG" a week for 4 months. Got my blood tested for the first time about 12hrs after my the most recent 100mg Text...
  24. Robotics

    Low Libido, Low SHBG Protocol HELP - LABS x3

    Has anyone dealt with something similar? Libido seems to be illusive and hard to find. I am a low SHBG and struggle with libido/erections. daily injector IM (9mg x 7 = 63 mg week) The only time I have felt normal in that sense (libido) is usually when I am coming off TRT (for a week or two). Or...
  25. J

    Global shortage of estradiol

    The Guardian is reporting a global shortage of estradiol. This affects both HRT and contraception. The focus of the article is on a current shortage in Australia and New Zealand. Perhaps disruption of the supply chain by covid-19, perhaps something else. "The affected products are distributed...
  26. S

    Some success, some challenges w/ daily protocol

    On the advice of Defy I switched to a daily protocol 12 weeks ago. I was on 140 mg of test (70 mg twice a week) and 150 IU/day of HCG. I now inject 18 mg of test daily w/ no change to HCG dose. I just ran my first labs after 12 weeks. In terms of side effect management it has been a complete...
  27. B

    Is low Estradiol (Naturally) along low free T effectively hypogonadism?

    I was reviewing blood tests from back when I was still natural in 2016. Total T in the 800s, single digit free T (pg/mL), E2 around 10 pg/mL. Then I started using steroids for about 18 months, hopped off. Total T in the 600s, free T and E2 around 12 pg/mL. I’m 10% fat year round. I’ve tried...
  28. B

    Question about estradiol

    Hello guys, I have made two estradiol tests in two different labs near the same dates. Results: 33.79pg/ml with electroquimioluminiscense method (11.3-43.2 lab ranges) 49pg/ml with Fluorescence Polarization ImmunoAssay (0-75pg/ml lab ranges) Note that the first one is a Lab that is the most...
  29. J

    Nipple soreness

    Hello everyone I am 9 months on my trt I've had three sets of blood work done, my levels have been good on all three sets the most recent was about 3 weeks ago. Out of nowhere tonight I'm having very very very tender sore nipple on my left side, and I was curious if my estrogen levels are good...
  30. G

    Study shows same estradiol reduction by 1 mg versus 0.5 mg anastrozole in young men

    Hello I was Reading this article Estrogen Suppression in Males: Metabolic Effect It says 0.5mg and 1mg arimidex has the same effect in estradiol
  31. Jman223

    How long after starting Arimidex should I draw labs

    Hello All, I recently switched Dr.s who recommended that I try Arimidex because my E2 is a bit high. I am well aware of the pros and cons and used to be a patient of Dr. Rob Kominerek so I understand the two sides of the debate. I reluctantly agreed to try .25 twice a week on shot day. Since...
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