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  1. O

    Estradiol valerate experiment .

    I have used transdermal as well but never got anything . It's only woth a synthetic progesterone that I have noticed textbook benefits of progesterone. Also experienced a boost in cortisol ( my knees and most joints forgot to ache just after 3-4 doses of BC pills) Also my urine stream has more...
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    Estradiol valerate experiment .

    When one comes across side effects ( like migraine) , he's ought to modify if not for better. Now bad protocols ( one which are invasive ) are difficult to adhere to, and are destined to fail ( even if it somehow works) . So finding a sustainable solution is also amongst priorities. My standard...
  3. O

    Estradiol valerate experiment .

    100 mg Test e split twice a week 1000 iu HCG EOD
  4. O

    Estradiol valerate experiment .

    Day 5 on BC pill Improvements Vision is clear than ever Joints feel so good . It's as if my knees have grown back . Lethargy has gone down, but not vanished Scalp is less dry EQ is better but far from good. Anxiety is down drastically. On another note I had a word with a gynecologist who...
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    Estradiol valerate experiment .

    No prescription in my country all along . Literally our version of "war on drugs"
  6. O

    Estradiol valerate experiment .

    Appreciate your feedback
  7. O

    Estradiol valerate experiment .

    In the quest for better, I am just collecting data
  8. O

    Estradiol valerate experiment .

    No . It's a parallel experiment to check HCG dose dependent rise in 17 OH progesterone .
  9. O

    Estradiol valerate experiment .

    @Gman86 @Cataceous So taking estrogen pill wasn't my original idea . I saw it on another forum (not sure if I am allowed to post links from another website) and a renowned youtuber also suggested it as well. So I found out why I was getting low estrogen symptoms even after taking estradiol...
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    Estradiol valerate experiment .

    I think I am doing something wrong here . Either I am taking too low of estradiol valerate or missing out on something. Thinking of trying combination birth control pills (ethinyl estradiol + levonorgestrel) for a week or so . I will post reports accordingly.
  11. O

    Estradiol valerate experiment .

    So one week on 0.5 mg eod estardiol valerate tablet, my SHBG didn't even blink . Headaches have become daily part of life . Skin got dried out even further Joint pain increased Hair fall increased .
  12. O

    Estradiol valerate experiment .

    It's faster in my country.
  13. O

    Estradiol valerate experiment .

    So I spoke to a woman (post menopausal) and she was on e2 replacement. She said headache happens when her e2 is high. Taking clues, I got my blood tested (trough values) For Estradiol ( ECLIA) Prolactin ( since it is a proxy for high estrogen as I read on forum) Total testosterone Results...
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    Estradiol valerate experiment .

    On a different note, I have read about the post regarding half life/ elimination life of HCG being different for doses (article compared 250 iu and 500 iu , I suppose) and that 500 iu had greater half life than 250 iu hcg. If we were to stretch this theory, is it possible that 1000iu hcg will...
  15. O

    Estradiol valerate experiment .

    I will incorporate 50 mg twice a week initially. Day 3 of e2V . Observation Intermittent headaces Significant appetite supression. Strong repulsion for sweets Feeling a bit hyperventilated Subtle ease in neck and shoulder stiffness.
  16. O

    Estradiol valerate experiment .

    Saturday April 20, 2024 Low SHBG Male ( 15-20) Currently on 200 mg test e (split 2 times a week) HCG 500 iu EOD Typical low estradiol symptoms like joint pain, dry skin, ED etc despite E2 in the range E2 ( non sensitive ) - 45 pg/ml (above range) Free T and DHT run above range I have...
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    Trt-clomid-low shbg

    Same old low SHBG, low E2 symptoms - Joint pain - brittle hair - dry skin - low libido - ED - Fat gain around mid section - loss of muscle tone - excercise intolerance - crippling fatigue - anhedonia - hyperventilation/ shortness of breath - Temperature fluctuations ( feet and hand always cold...
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    Trt-clomid-low shbg

    So 100 mg per week of test e should be fine, right ? I guess HCG would also contribute to some testosterone and I would still be in higher end of the range . I just started estradiol valerate today . Would it make sense to get blood tested tomorrow?
  19. O

    High DHT converter... becoming a problem for me

    Any ballpark figure for Estradiol valerate oral dose ?
  20. O

    Trt-clomid-low shbg

    I am currently at 200 mg test e weekly with 500 iu EOD HCG . How much do you suggest I should go with to reduce DHT ? Also started with 1 mg E2 valerate today . Having a bit of palpitations and headaches. Have I taken too much or should I wait for it to adjust ?
  21. O

    Trt-clomid-low shbg

    To be honest I don't know how much I can rely on labs , coz I have mentioned before that labs in my country use ECLIA n not equilibrium dialysis. Don't know if the whole ratio thing applies to me . My broader Target is to try increase my SHBG and see if it helps .
  22. O

    Trt-clomid-low shbg

    Ok great . I will initially go with e2V oral just to check if it helps with symptoms and SHBG levels, hopefully 4 weeks @ 1mg everyday . Will this affect the normal range of total T to E2 ratio I should be looking for ? Where shall that ratio lie according to you ? I also recollect Nelson...
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    Trt-clomid-low shbg

    I am not good enough at science as you, but I read on some forum regarding oral estradiol valerate leaving less of the estrone metabolite (supposedly bad ) than injectable estradiol. Also read that only oral estradiol valerate is good at bumping up SHBG. One of the forum's said you need to take...
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    Trt-clomid-low shbg

    Can you suggest Estradiol valerate oral dose ? I have low estradiol (in 20s on 200 mg a week of test e and 500 iu HCG EOD protocol. Off the chart freeT and DHT. SHBG 20-25 ) Would it be any better to take estradiol valerate in injection form ?
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    How to co relate RIA and equilibrium dialysis reports

    My SHBG is 22 And total testosterone 5.72 ng/ml but these are tested with ECLIA method . Can they be used as valid entity in calculator ?
  26. O

    How to co relate RIA and equilibrium dialysis reports

    Sorry, I didn't understand the complexity of your last sentence . Are you trying to say RIA gives exaggerated values as compared to equilibrium dialysis ?
  27. O

    How to co relate RIA and equilibrium dialysis reports

    Problem is that they use same RIA method for SHBG and total testosterone as well . So I guess everything becomes unreliable now. Lol Btw does RIA gives exaggerated values compared to equilibrium dialysis ?
  28. O

    How to co relate RIA and equilibrium dialysis reports

    I don't have equilibrium dialysis assay in my country and they test free testosterone with RIA or CLIA method only So my recent free testosterone (RIA method) was 49 pg/ml ( 12-40 pg/ml) This says I am over the reference range . Should I take this for face value or assume the assay is flawed ...
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    HCG effects on TSH

    What was your hcg dose when you felt like it increased tour thyroid activity?
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