I have used transdermal as well but never got anything . It's only woth a synthetic progesterone that I have noticed textbook benefits of progesterone. Also experienced a boost in cortisol ( my knees and most joints forgot to ache just after 3-4 doses of BC pills)
Also my urine stream has more...
When one comes across side effects ( like migraine) , he's ought to modify if not for better.
Now bad protocols ( one which are invasive ) are difficult to adhere to, and are destined to fail ( even if it somehow works) . So finding a sustainable solution is also amongst priorities.
My standard...
Day 5 on BC pill
Improvements
Vision is clear than ever
Joints feel so good . It's as if my knees have grown back .
Lethargy has gone down, but not vanished
Scalp is less dry
EQ is better but far from good.
Anxiety is down drastically.
On another note
I had a word with a gynecologist who...
@Gman86 @Cataceous
So taking estrogen pill wasn't my original idea . I saw it on another forum (not sure if I am allowed to post links from another website) and a renowned youtuber also suggested it as well.
So I found out why I was getting low estrogen symptoms even after taking estradiol...
I think I am doing something wrong here .
Either I am taking too low of estradiol valerate or missing out on something.
Thinking of trying combination birth control pills (ethinyl estradiol + levonorgestrel) for a week or so .
I will post reports accordingly.
So one week on 0.5 mg eod estardiol valerate tablet, my SHBG didn't even blink .
Headaches have become daily part of life .
Skin got dried out even further
Joint pain increased
Hair fall increased .
So I spoke to a woman (post menopausal) and she was on e2 replacement. She said headache happens when her e2 is high.
Taking clues, I got my blood tested (trough values)
For
Estradiol ( ECLIA)
Prolactin ( since it is a proxy for high estrogen as I read on forum)
Total testosterone
Results...
On a different note, I have read about the post regarding half life/ elimination life of HCG being different for doses (article compared 250 iu and 500 iu , I suppose) and that 500 iu had greater half life than 250 iu hcg.
If we were to stretch this theory, is it possible that 1000iu hcg will...
I will incorporate 50 mg twice a week initially.
Day 3 of e2V . Observation
Intermittent headaces
Significant appetite supression. Strong repulsion for sweets
Feeling a bit hyperventilated
Subtle ease in neck and shoulder stiffness.
Saturday April 20, 2024
Low SHBG Male ( 15-20)
Currently on 200 mg test e (split 2 times a week)
HCG 500 iu EOD
Typical low estradiol symptoms like joint pain, dry skin, ED etc despite E2 in the range
E2 ( non sensitive ) - 45 pg/ml (above range)
Free T and DHT run above range
I have...
Same old low SHBG, low E2 symptoms
- Joint pain
- brittle hair
- dry skin
- low libido
- ED
- Fat gain around mid section
- loss of muscle tone
- excercise intolerance
- crippling fatigue
- anhedonia
- hyperventilation/ shortness of breath
- Temperature fluctuations ( feet and hand always cold...
So 100 mg per week of test e should be fine, right ? I guess HCG would also contribute to some testosterone and I would still be in higher end of the range .
I just started estradiol valerate today . Would it make sense to get blood tested tomorrow?
I am currently at 200 mg test e weekly with 500 iu EOD HCG . How much do you suggest I should go with to reduce DHT ?
Also started with 1 mg E2 valerate today .
Having a bit of palpitations and headaches. Have I taken too much or should I wait for it to adjust ?
To be honest I don't know how much I can rely on labs , coz I have mentioned before that labs in my country use ECLIA n not equilibrium dialysis. Don't know if the whole ratio thing applies to me . My broader Target is to try increase my SHBG and see if it helps .
Ok great .
I will initially go with e2V oral just to check if it helps with symptoms and SHBG levels, hopefully 4 weeks @ 1mg everyday . Will this affect the normal range of total T to E2 ratio I should be looking for ? Where shall that ratio lie according to you ?
I also recollect Nelson...
I am not good enough at science as you, but I read on some forum regarding oral estradiol valerate leaving less of the estrone metabolite (supposedly bad ) than injectable estradiol.
Also read that only oral estradiol valerate is good at bumping up SHBG.
One of the forum's said you need to take...
Can you suggest Estradiol valerate oral dose ? I have low estradiol (in 20s on 200 mg a week of test e and 500 iu HCG EOD protocol. Off the chart freeT and DHT. SHBG 20-25 )
Would it be any better to take estradiol valerate in injection form ?
Sorry, I didn't understand the complexity of your last sentence . Are you trying to say RIA gives exaggerated values as compared to equilibrium dialysis ?
Problem is that they use same RIA method for SHBG and total testosterone as well . So I guess everything becomes unreliable now. Lol
Btw does RIA gives exaggerated values compared to equilibrium dialysis ?
I don't have equilibrium dialysis assay in my country and they test free testosterone with RIA or CLIA method only
So my recent free testosterone (RIA method) was 49 pg/ml ( 12-40 pg/ml)
This says I am over the reference range . Should I take this for face value or assume the assay is flawed ...
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