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Empower FDA Warning Letter
Have you guys seen this? https://www.fda.gov/inspections-compliance-enforcement-and-criminal-investigations/warning-letters/empower-clinic-services-llc-dba-empower-pharma-700962-04022025 Not a good look!- FunkOdyssey
- Thread
- empower pharmacy
- Replies: 1
- Forum: Compounding Pharmacy Product Reviews
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Took 4 days off my EOD injections and feel great. Need advice
Absolutely, yes. The idea that SHBG predicts what injection frequency will be optimal for you is an old wives' tale.- FunkOdyssey
- Post #6
- Forum: Testosterone Basics & Questions
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Took 4 days off my EOD injections and feel great. Need advice
It's a reasonable thing to try, among many other reasonable things to try (different esters/formulas, different injection methods/sites/depths, other forms of TRT like topical and oral). You would like accurate predictions about how you will respond to these various interventions, to save...- FunkOdyssey
- Post #3
- Forum: Testosterone Basics & Questions
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New To TRT - Compounded Cream Sides
There isn't enough emphasis on the fact that weird and unpleasant symptoms are quite possible when starting TRT, which are likely temporary, and shouldn't be interpreted to mean you cannot tolerate TRT generally or even the particular form you're using. I'm certain I also reached a bunch of...- FunkOdyssey
- Post #9
- Forum: Testosterone Side Effect Management
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Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more
We suggest once per day dosing because it is simple and effective for the majority of patients. Some 10% of patients seem to prefer twice daily dosing, so it can be worth experimenting with. It may seem counterintuitive, but there is often no strong relationship between your serum level of...- FunkOdyssey
- Post #49
- Forum: Blood Test Discussion
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Dosage for women's testosterone ?
No, it's not possible that injections will fail to raise her levels. If you inject subq, maybe a percentage is lost to the void like sometimes happens with test, but in that case you just inject more. The levels will come up. 1.2 mg estradiol cypionate EOD, 299 pg/ml total E2, 3.56 pg/ml free...- FunkOdyssey
- Post #17
- Forum: HRT in Women
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Dosage for women's testosterone ?
Cypionate or enanthate. We started with E3.5D but had better results with EOD cypionate.- FunkOdyssey
- Post #15
- Forum: HRT in Women
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Dosage for women's testosterone ?
For many women, estradiol doesn't help until you reach 200+ pg/ml - lesser administration methods and mainstream docs will rarely get you there. Beware of elevated SHBG, which increases the total E2 they need to feel good, just like testosterone.- FunkOdyssey
- Post #13
- Forum: HRT in Women
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Dosage for women's testosterone ?
There's always a way. https://hrtcafe.net/Estrogen/estradiol_injections.html- FunkOdyssey
- Post #10
- Forum: HRT in Women
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Dosage for women's testosterone ?
These increase clotting risk and are not very effective. You want estradiol injections if you can get them, or failing that, transdermal E2. If you can't find a doctor to play ball, the trans community is an excellent source for high quality UGL estradiol in many countries. Don't supplement E2...- FunkOdyssey
- Post #8
- Forum: HRT in Women
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Dosage for women's testosterone ?
Less testosterone was more, and estradiol was more effective for sexual function and libido in our case. Under normal physiologic conditions / hormone levels, estradiol is the primary driver of libido in female mammals of all stripes including humans. Testosterone plays more of a complimentary...- FunkOdyssey
- Post #3
- Forum: HRT in Women
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Can we talk about low dose daily tadalifil
I thought this too, until I found evidence that tadalafil is substantially more protective than sildenafil. This seems consistent with it's longer half life, supporting the hypothesis that these medications are actually beneficial. Unless of course, you can think of a reason the populations of...- FunkOdyssey
- Post #10
- Forum: Testosterone Basics & Questions
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Second Opinion on Restarting TRT (Primary Hypogandism)
These can be fixed by things like lower dose and/or switch to daily test propionate. There are likely some benefits to maintaining normal HPTA function, but it wasn't necessary in my case to resolve your entire list of complaints.- FunkOdyssey
- Post #8
- Forum: Testosterone Side Effect Management
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Kyzatrex vs Maximus Native T
No, I was there. What point are you trying to make? Not one of us emerged from the womb knowing what native testosterone was, not even you good buddy.- FunkOdyssey
- Post #11
- Forum: Testosterone Basics & Questions
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Kyzatrex vs Maximus Native T
Here's your question as I read it: aside from clinically significant differences in side effects, have clinically significant differences been found? Yes, there are also differences in fasted absorption, and the amount of DHT that results, where native testosterone produces a lower DHT:T ratio...- FunkOdyssey
- Post #7
- Forum: Testosterone Basics & Questions
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Kyzatrex vs Maximus Native T
I misread that, sorry. Consult with your Maximus provider, but yes, that works fine in many cases. Roughly 90% of patients stay with the single morning dose and 10% opt for split dosing like you're proposing.- FunkOdyssey
- Post #5
- Forum: Testosterone Basics & Questions
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Kyzatrex vs Maximus Native T
They are not the same thing. Native testosterone is simply testosterone without chemical modification. Testosterone undecanoate modifies testosterone by attaching the undecanoate ester. Cue someone rushing to reply, "but testosterone undecanoate yields the same bioidentical testosterone...- FunkOdyssey
- Post #3
- Forum: Testosterone Basics & Questions
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Trouble Finishing (GLP-1 & TRT protocol discussion)
The obvious answer here is to gradually reduce the dose of tirzepatide, until you find a dose that controls your weight without making climax impossible. Like TRT, a series of dosage adjustments are typically required with GLP-1 medications to reach an optimal state of benefits vs. side effects...- FunkOdyssey
- Post #13
- Forum: Testosterone Basics & Questions
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Primary Hypogonadism: Doctor wants to put me on 25mg of Testosterone enanthate per week
Oral testosterone would be my vote for this guy. Equalized for a target LH / FSH level, you'll be able to hit high peak levels with oral testosterone, whereas your non-fully-suppressive dose of injections will probably produce peak levels that are on the low side of the normal range. Either...- FunkOdyssey
- Post #16
- Forum: Testosterone Basics & Questions
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Need honest advice: Do I really need TRT? Low-normal T, low libido for years, anxiety/OCD background, little muscle growth
Absolutely, yes. Psychology doesn't prevent gym gains. The other symptoms may possibly have a psychological component, or they could be testosterone related. Life-changing is a little too strong in my case. Very beneficial would be a more apt description. Yes, it could.- FunkOdyssey
- Post #5
- Forum: Testosterone Basics & Questions
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Lab results seem way too high
Yeah, yeah. You live (usually) and learn.- FunkOdyssey
- Post #22
- Forum: Testosterone Basics & Questions
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Lab results seem way too high
You know what's likely to help with the lumps, and is missing from your list of experiments? Injecting half the dose / volume!- FunkOdyssey
- Post #18
- Forum: Testosterone Basics & Questions
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Lab results seem way too high
Your lab numbers are real and expected. 28 mg of test prop daily is a heroic dose, regardless of what you heard elsewhere, and I have put up similarly insane and unsustainable numbers with similar doses. These days, I take exactly half of that (14 mg daily). Much better results in terms of...- FunkOdyssey
- Post #13
- Forum: Testosterone Basics & Questions
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Help me make up my mind about a change in protocol
Yes, they are more expensive. I use tigermedical.com, which is not the cheapest option, but its one that doesn't enforce the CT laws requiring a prescription for the syringes.- FunkOdyssey
- Post #12
- Forum: Testosterone Basics & Questions
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Help me make up my mind about a change in protocol
BD for everything. Easy touch is not bad, but I think BD is better quality.- FunkOdyssey
- Post #10
- Forum: Testosterone Basics & Questions
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Help me make up my mind about a change in protocol
Yes. I tried 27G 5/8" for awhile when I was on an EOD testosterone cypionate in MCT protocol, but I feel these are too large for ED. My T/E ratio was actually way too high on that protocol, as high as ~60:1 at one point, so in some cases you might even take things too far with the "deeper IM...- FunkOdyssey
- Post #8
- Forum: Testosterone Basics & Questions
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Help me make up my mind about a change in protocol
Each site can be subdivided into many more mini-sites. You don't need to, nor should you IMO, inject into the bullseye center of these muscles everytime. Move all around. EOD is great for most people. Use a thicker viscosity formula for this if the most stable levels are your goal. This...- FunkOdyssey
- Post #3
- Forum: Testosterone Basics & Questions
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Any Testosterone Propionate Compounding Pharmacies left?
You did a good job bringing the issue of the raw shortage to light, and calling it early. Kudos again for that. Now you're acting hysterical. It's really not the end of the world, when the worst case imaginable is having to return to somewhat overpriced legit prescription sources. I doubt it...- FunkOdyssey
- Post #44
- Forum: Testosterone Basics & Questions
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I started with oral TRT with Maximus last week. I have a couple of questions....
Sounds like 35 - 40 grams of fat, which should be sufficient. No, but communicate with your provider before making any adjustments to your protocol.- FunkOdyssey
- Post #4
- Forum: Testosterone Basics & Questions
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