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There are a concerning number of reports, some of which you can find in other threads here, of people who tried TRT and had it change something about their dopamine/neurotransmitter pathways in a way that did not return to normal. I'm not aware of any reliable stats on this but it has certainly...

Clomid/Enclomiphese "tricks" the body into signaling for more T so it only has that affect while it's being used. Whether benefits would continue past its use is unknown for an individual but unlikely. Note that there are reports of people who messed themselves up, especially in the sexual...

My two cents...I think your thinking here is correct. No matter what your numbers some guys respond better than others and it is in your interest to see how you respond. You might be a good candidate for Clomid or Enclomiphene which is how I started. A low dose (12mg every other day) is low risk...

Stress and poor sleep could be an overall confounder both for your numbers and how you feel.

There are a number of posts here describing the Testosterone "pulse" therapy pioneered by Dr Samuel Denmeade where he uses periodic high doses of T (I seem to remember something like 600mg of Test Prop every 6 weeks, or something like that) as anti-Prostate cancer therapy. I've wondered about...

Thanks for the update. We don't get enough long-term updates here. I hope you have a complete, speedy and permanent recovery.

It sounds like starting with Enclomiphene or Clomid at a low dose (e.g. `12mg every other day, for example) might be a good first step since your natural production would, if anything, increase. Lithium Orotate or Acetate is also know to help with stress. Regarding test suspension, you would...

A lot of the answer here depends on what your priorities are. Are you trying to maintain fertility? If so I expect you would want HCG in the mix. Are you trying to improve athleticism? Low dose Oxandrolone might be a better option. Is mood the priority? Test suspension might do what you need...

I agree that traditional bulking and cutting is a bad idea (it runs totally counter to the principle of consistency, which is the number one problem for most people) but varying diet within a weekly timeframe works well for me. I focus high protein in the 18 hours after a heavy workout and then...

If I'm interpreting this correctly, it sounds like your SIBO and digestive issues are still unresolved. That could cause so many other issues that IMO you need to get that completely resolved first and then see where you stand with the rest of your health. There are options beyond anti-biotics...

I agree with everything Nelson said. For general pain, Boswellia extract has made a difference for me, and full-strength basic aspirin is often overlooked but is also quite effective and relatively safe for most people. Some people benefit from XXX oil capsules. I find diclofenac effective for...

There are apparently confounders that raise creatinine like creatine use and possibly recent hard exercise. eGFR is a calculated number IIRC and is based off of creatinine. I use the cystatin C test which is apparently much more accurate. There is another test I have forgotten the name of which...

I'm least familiar with AH of the people above but I'm suspicious of people who didn't get kicked off of YouTube during covid, and his recent anti-alcohol focus is IMO off-base on a number of points as Chris Masterjohn and Mark Sisson among other have also pointed out. The common thread I...

Inability/unwillingness to do a background check from credible (non-mainstream) sources and/or use a search engine to do the due diligence Joe Rogan claims to have done in a matter of minutes also partially explains some very high-risk/low-reward health advice. And that's assuming nothing worse...

While there are some worthwhile things here, this shows the problem with mainstream influencers who are really gatekeepers for mainstream medicine. Every health intervention needs to start with removing the cause of the problem, which in the case of cognitive issues is IMO best captured by Dr...

This is a fantastic resource! Another type of FAQ list to consider (although perhaps too controversial) are considerations for selecting a provider since we see many posts from people who seem to be getting guidance from biased or narrow-thinking providers. Some examples could be: - Option...

I looked at Akina's site and there was no mention of this product. I have not had time to reach out to them but they don't look like they are easy to do business with from my first impression.

I'm happy to hear you're making progress. I looked back through this thread and I didn't see whether you have tried BPC patches (not injections, not oral). I've tried a bunch of things for what I think is a combination of a sciatic nerve issue and a hip joint issue, and the patches seem to be...

yes.

1700mg per day is, to me, an insanely and unnecessarily high dose. Constant use would make it worse. I use 250mg of metformin (or berberine) prior to a high carb meal, and that is only once or twice per week. I also try to make sure I have some light activity after such a meal which further...

I've seen other Doctors (e.g. Elizabeth Yurth) make the case that the best way to raise NAD is to reduce the enzyme that breaks NAD down (which Apigenin does, among other things.) It doesn't look like they cover that here.

I'm well aware, however my approach to lack of authenticity, whether human or machine (which, sadly, is becoming more common in both cases) is to respond with authenticity, which will hopefully encourage authentic responses from someone and benefit other readers. I'm actually kind of glad the...

Nandrolone seems to help all around, however BPC and DMSO are my primary go-to's for joint pain, but I like having a small amount of N in the mix as well. As far as troches go, I always like to look for ways to improve and I seem to feel fractionally better when my T is at a trough, so perhaps...

I'm glad it's working for you, but there are some other important considerations that I think the wider population of people on or considering TRT would want to take into account. - Injections and creams have decades of crowdsourced knowledge about how to fine-tune them for an individual...

I've used Oxandrolone as an adjunct for a number of years and have a few observations. - If you're not already close to your genetic limits before starting, the benefits may not be distinguishable from what you would have gotten from simply continued consistent training, unless you are using...

While I would never suggest that someone start drinking and I've seen the damage that comes from people having a bad relationship with alcohol (or other addictions), the recent anti-alcohol push seems deceptive on several fronts. First, most of the articles say "as little as 1-2 drinks per day...

One of the best hernia Docs is apparently in Jacksonville FL. If you search on the Mercola.com site you should find an interview with him. Dr. Mercola had a hernia and that is who he used. Yours may be a different type but it sounds like it is worth watching. The main thing I remember is that...

Thanks for publicizing this. Have you found any reports of its effect on PSA or cancer-related impacts in general?

That looks like a great starting plan to me and you can adjust based on how you feel. There's nothing wrong with a 9 or 10 day "week". That's how I used to train when I had the schedule flexibility. Some people do well on low carb and some don't. I find that I can get fairly lean on 100-300...

Regarding calories, the whole point is to reduce overall calories while maintaining your metabolic rate, so the first question is whether your metabolic rate has already declined due to chronic calorie restriction or whether you are at a maintainable steady state. To be safe you could add 100...

A few ideas. First, congratulations on the progress you've made so far! You're way ahead of many people. - For diet in general, I recommend people use the book Perfect Health Diet by Paul Jaminet as a home base, but it sounds like you are fairly close to what he recommends. - IME seed oils are...