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  1. D

    SHBG: who has successfully lowered their levels?

    Sorry I'm late to the party. Just had my first SHBG panel in about a year. Update: Managing my TAT symptoms with 4mg of Anastrazol a week, 12.5g clomid every 10 days, and 75-150mg of armadofinil daily if needed. Armadofinil keeps me normal, exactly how I want to feel but I grind my teeth...
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    AI needed in 1/6 men on clomid

    Ive been on Clomid/Anastrazole for almost 2 years. Clomid keeps me from falling asleep at the dinner table, anastrazole keeps the bloating down. Labs are optimal (600-900 Total T with good E2 ratio to Free T, normal SHBG) 12.5 mg clomid/4mg AI weekly. I feel mediocre on this regimen and...
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    Possible false HIGH total testosterone blood test level?

    Sorry for the late repsons. Ive read and heard for years about TD false readings due to TD gel on the cubital fossa spiking the assay.
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    Is Testosterone to Estradiol Ratio Important in Men?

    I think these are good general guidelines Nelson, however Ive been going through an opposite scenario. For over a year Ive been on a Clomid titration from 25mg EOD to now 12.5 twice a week. TT has been in the range of 900-1100 with high estradiol numbers, Always felt shitty for a long time...
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    Possible false HIGH total testosterone blood test level?

    What are your application sites? Are you rubbing the TD onto your forearm where they are drawing from?
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    Thoughts on Progesterone

    Higher SHBG and E2 typically signs your liver likes to convert. Would it be out of the question to drop DHEA, Chrysin, and pass on the progesterone for now? (DHEA converts via pathway that sidesteps AIs). See how you feel on TD and vitamins, simple and definitely cheaper. Draw labs in 8...
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    Any Anonymous Sleep Studies to recommend?

    Google term life insurance.
  8. D

    Oxytocin

    Prolactin is the show stopper in this post event cascade.
  9. D

    DHEA Supplementation in Men: What Do Studies Show?

    Hey Nelson et al, thanks for the links. I've been interested in finding out more about this backfill procedure with DHEA/Preg. DHEA makes me a little edgy anxious and my numbers are upper quartile. Also I believe the estrogen conversion goes through a pathway that bypasses AIs. Trying to learn...
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    Any Anonymous Sleep Studies to recommend?

    Good idea, thanks Nelson!
  11. D

    Any Anonymous Sleep Studies to recommend?

    I'd like to test for sleep apnea, don't want it on my chart for insurance reasons. Anyone use discreet sleep study at home or lab? Thanks!
  12. D

    Lab Tests: What Do They Mean?

    I believe that as well Nelson. Could've gone without the glutathione, love it when oral precursor actually works!
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    List of Nootropics: Brain supplements and medications to increase focus and mood.

    I only get good SAMe results from the Jarrow formulation, this stuff is good. DHEA puts me on the edge a bit, levels are in the upper quartile but it makes me a bit moody. I'll have to try your sleep my stack, looks good.
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    List of Nootropics: Brain supplements and medications to increase focus and mood.

    Thanks Nelson. Trying to put together a "Alertness/Cognition" Stack as well as a "Sleepy" Stack (non-prescription/OTC, simple, cheap). Anyone use powdercity.com or have a better sourcing reference? Thanks!
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    23, one month Androgel, bloodwork all over the place!

    What were your primary symptoms? It has suggested that applying transdermals with your hands, there is a transfer loss in your palms. Your ferritin pretty low, which sometimes is associated with high volume training.
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    Injections not working

    If it ain't broke don't break it... Why did you switch in the first place? E2 is over range, what did it look like on gels?
  17. D

    Lab Tests: What Do They Mean?

    You've had some recent stress to your liver which caused the elevated enzyme level. I've had the same with a bout of food poisoning, solved it with short term glutathione injections and daily NAC... Levels are back in the 30s.
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    TRT has been underwhelming for 4+ years - Low SHBG

    What other protocols do you follow being a hyper-excreter? I.e. Estrogen management, HCG, sub-q delivery etc. Doc Crisler has a lot info regarding cases similar to yours.
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    Dopamine, Prolactin and Sex

    Thank you Nelson for getting the ball rolling in this topic. I think this is at the root of secondary hypo and why we don't see therapeutic responses with Clomid. I suspect dysfunction upstream in the Hypo-Pitu area that SERMs do not address in their mechanism even though my numbers on paper...
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    Help, feeling emotional

    What else are u taking beside the AI?
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    Aromatase inhibitors other than arimidex?

    Dug up, interested in the effects of Aromasin vs Anastrazole. Ive been on 3mg/week of Anastrazole with 51 pg/ml E2s assay (high over 35pg/ml) with ~30mg of Clomid/week. Also SHBG has come in consistently in the upper quartile. Tired, moody and defintely efficient at aromatizing. If...
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    Recent blood tests don't match up

    What time (AM/PM) are your draws at?
  23. D

    23 year old, low T, this is my story! Clomid??? Please help!

    Two more things: -Prolactin levels can spike and skew if you had sex the night before the test. Google search for the exact time parameters, the TRT docs know about this. May not need an MRI if this is the case. -If your DHEA levels are over parameter, you might be taking in DHEA in one of...
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    23 year old, low T, this is my story! Clomid??? Please help!

    The combination of low T and Iron/Ferritin may be a sign of training exhaustion. Athletes that cut cardio back and replace with a strength block typically recover their T numbers. Still on Clomid and don't regret it (I'm definitely secondary). It's a good test to see how your axis is holding up...
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    23 year old, low T, this is my story! Clomid??? Please help!

    Mid 30s here, multi-sport athlete Clomid looks great on paper, but I rarely feel great and sex drive/ erections are nothing to write home about. Do you have or have you ever had a porn addiction or watch porn regularly?
  26. D

    Defy Medical

    Im on the other coast and a Defy paitent. Dr. Saya is sharp, every question I had about panel numbers he addressed without asking and had logical answers and reasoning. Definitely the way to go!
  27. D

    Does Modafinil Work For Energy?

    Im assuming youre talking hormone numbers, what type of HRT on you administrating? I use Nuvigil in combination with 25mg of Clomid+AI. I can get by with just Clomid, not sleepy but not really motivated to do anything. Ive taken Nuvigil without Clomid for a few days and fell asleep 2 hours...
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    Does Modafinil Work For Energy?

    On Nuvigil. I'm 100kg and 75mg-100mg is the right range for me. Low dose is very subtle, about two clicks below being fully wired. Try to take the 3rd day off to help clearance, I notice increased heart rates and altered sleep patterns when I dose longer than 48 hours and more than 300mg...
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    Can Testosterone Cause Retinopathy?

    Do you have lab values during HRT?
  30. D

    Tried Clomid restart, doc has me on hCG mono now...

    Did you consider low dose clomid (i.e. 12.5 ED or EOD) Might not need an AI with this route.
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