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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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<blockquote data-quote="Gman86" data-source="post: 267649" data-attributes="member: 15043"><p>Ya sounds like u just has a combo of high prolactin and low dopamine going on. That combo can absolutely kill sex drive, and make u feel depressed and moody and just like crap in general. I’m just not sure if the nandrolone can lower dopamine simply by raising prolactin, or if there’s another mechanism by which it can mess with dopamine. I’m hoping it’s simply the former. At least we have pretty straight forward ways of lowering prolactin. Whether it’s via a DHT derivative that lowers E2, and consequently tends to lower prolactin as well, or whether it’s with something like selegiline. Obv prami and caber lower prolactin as well, but I’m just not sure about the long term risks of using either of those. I personally feel more comfortable using something like selegiline and/ or low doses of primo or Proviron</p><p></p><p>if nandrolone affects dopamine negatively in another way, that we’re not aware of, then that’s worse, imo. Simply because if we don’t know how it’s lowering dopamine, we really don’t know how to try and resolve the issue if it happens</p></blockquote><p></p>
[QUOTE="Gman86, post: 267649, member: 15043"] Ya sounds like u just has a combo of high prolactin and low dopamine going on. That combo can absolutely kill sex drive, and make u feel depressed and moody and just like crap in general. I’m just not sure if the nandrolone can lower dopamine simply by raising prolactin, or if there’s another mechanism by which it can mess with dopamine. I’m hoping it’s simply the former. At least we have pretty straight forward ways of lowering prolactin. Whether it’s via a DHT derivative that lowers E2, and consequently tends to lower prolactin as well, or whether it’s with something like selegiline. Obv prami and caber lower prolactin as well, but I’m just not sure about the long term risks of using either of those. I personally feel more comfortable using something like selegiline and/ or low doses of primo or Proviron if nandrolone affects dopamine negatively in another way, that we’re not aware of, then that’s worse, imo. Simply because if we don’t know how it’s lowering dopamine, we really don’t know how to try and resolve the issue if it happens [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
What is the reason that nandrolone causes depression? (Mechanism of action)
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