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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What is the best dose of HCG? Dr Saya presents two case studies.
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<blockquote data-quote="madman" data-source="post: 209251" data-attributes="member: 13851"><p>He would have stated such seeing as the Leydig cells only make up 10-20% of testicular volume.</p><p></p><p>Much more to the story.</p><p></p><p>hCG mimics LH which stimulates the Leydig cells to produce ITT (intra-testicular testosterone).</p><p></p><p>Although the Leydig cells become dormant/atrophy without stimulation from LH/LH analog you would think that testicular shrinkage would be minimal.</p><p></p><p>Unfortunately when using exogenous T not only is their lack of LH but also FSH which is needed to stimulate Sertoli/germ cells to produce sperm.</p><p></p><p>Seminiferous tubules are made up of Sertoli cells and germ cells and the reduction of these cells results in testicular atrophy which reflects the loss of both spermatogenesis and Leydig cell function.</p><p></p><p>Hope you understand that when using/abusing testosterone let alone AAS testicular atrophy can be significant and extreme in some cases since 80% of the testicular volume is made up of germ cells/seminiferous tubules.</p><p></p><p>Even though the use of hCG will stimulate Leydig cells to produce ITT you need to keep in mind that <u>ITT will also have an impact on Sertoli/germ cells and can still contribute to preventing/minimizing overall testicular atrophy let alone improve sperm production</u>.</p><p></p><p>The addition of FSH would have a greater impact on preventing/minimizing the degree of testicular atrophy let enhancing sperm production.</p><p></p><p>Use of hCG whether solo (monotherapy) or with exogenous T will still have a big impact on preventing/minimizing testicular atrophy let alone sperm production.</p><p></p><p>Would not put too much weight behind the.....<strong><em>HCG only has effect on 20% of the testicle so adjust your expectations</em></strong></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/when-testicle-size-increases-what-happens.20913/#post-176632[/URL]</p><p></p><p></p><p><strong><em>[ATTACH=full]16804[/ATTACH]</em></strong></p><p>[ATTACH=full]16806[/ATTACH]</p><p></p><p></p><p></p><p><strong>Fig. 9 Testicular atrophy in a 30-year old AAS abuser (right) compared to normal size (left)</strong></p><p>[ATTACH=full]16807[/ATTACH]</p></blockquote><p></p>
[QUOTE="madman, post: 209251, member: 13851"] He would have stated such seeing as the Leydig cells only make up 10-20% of testicular volume. Much more to the story. hCG mimics LH which stimulates the Leydig cells to produce ITT (intra-testicular testosterone). Although the Leydig cells become dormant/atrophy without stimulation from LH/LH analog you would think that testicular shrinkage would be minimal. Unfortunately when using exogenous T not only is their lack of LH but also FSH which is needed to stimulate Sertoli/germ cells to produce sperm. Seminiferous tubules are made up of Sertoli cells and germ cells and the reduction of these cells results in testicular atrophy which reflects the loss of both spermatogenesis and Leydig cell function. Hope you understand that when using/abusing testosterone let alone AAS testicular atrophy can be significant and extreme in some cases since 80% of the testicular volume is made up of germ cells/seminiferous tubules. Even though the use of hCG will stimulate Leydig cells to produce ITT you need to keep in mind that [U]ITT will also have an impact on Sertoli/germ cells and can still contribute to preventing/minimizing overall testicular atrophy let alone improve sperm production[/U]. The addition of FSH would have a greater impact on preventing/minimizing the degree of testicular atrophy let enhancing sperm production. Use of hCG whether solo (monotherapy) or with exogenous T will still have a big impact on preventing/minimizing testicular atrophy let alone sperm production. Would not put too much weight behind the.....[B][I]HCG only has effect on 20% of the testicle so adjust your expectations[/I][/B] [URL unfurl="true"]https://www.excelmale.com/forum/threads/when-testicle-size-increases-what-happens.20913/#post-176632[/URL] [B][I][ATTACH type="full" alt="Screenshot (7729).png"]16804[/ATTACH][/I][/B] [ATTACH type="full" alt="Screenshot (7731).png"]16806[/ATTACH] [B]Fig. 9 Testicular atrophy in a 30-year old AAS abuser (right) compared to normal size (left)[/B] [ATTACH type="full" alt="Screenshot (7732).png"]16807[/ATTACH] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
What is the best dose of HCG? Dr Saya presents two case studies.
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