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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
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<blockquote data-quote="tareload" data-source="post: 222623"><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/nandrolone-for-mood-feeling-much-better.25165/post-222614[/URL]</p><p></p><h3><em><span style="font-family: 'Georgia'"><em>Subjects and study design</em></span></em></h3><p><em><em><span style="font-family: 'Georgia'"><em>Study subjects included 27 healthy volunteers originated from the study population described in more detail elsewhere.<a href="https://www.excelmale.com/forum/javascript%3A;" target="_blank">14</a> All participants were males aged 18–50 years, with a body mass index (BMI) range of 18.2–28.7 (median value 24.3) who gave informed consent consistent with the approval of the Ethics Review Board. All subjects underwent a medical examination before enrolment to exclude any possible diseases. The participants were not taking any kind of substance that could interfere with testosterone metabolism and were tested negative for illegal drugs, AAS, HIV and hepatitis B or C. For inclusion it was also required that the subjects did not belong to the Swedish Sports Confederation nor had had a malignancy within the past five years.</em></span></em><span style="font-family: 'Georgia'"><em> The participants were given 500 mg testosterone enanthate as a single intramuscular dose (Testoviron®–Depot kindly provided by Schering Nordiska AB, Solna, Sweden) equivalent to 360 mg testosterone. The testosterone dose among AAS abusers varies depending on the purpose of their abuse and which other AAS they co-administrate, but most abusers report testosterone doses corresponding to 500–2000 mg testosterone enanthate/week. For safety reasons, we chose the lower dose in this range.</em></span><em><span style="font-family: 'Georgia'"><em> Before administration, a baseline morning urine sample was collected (day 0) and morning urine was further collected on days 1 and 2. The urine samples were collected and kept refrigerated for a maximum of 48 h and then frozen at −20°C. Adverse drug reactions (ADRs) were monitored from the time of screening until day 15 after administration of testosterone. No ADRs were registered and no follow-up was needed. The study was conducted according to the Helsinki declaration and the ICH Harmonized Tripartite Guideline for Good Clinical Practice, and was approved by the Ethic Review Board, Karolinska Institutet.</em></span></em></em></p><p></p><p></p><p></p><p></p><p>[URL unfurl="true"]https://www.excelmale.com/forum/threads/nandrolone-for-mood-feeling-much-better.25165/post-222597[/URL]</p></blockquote><p></p>
[QUOTE="tareload, post: 222623"] [URL unfurl="true"]https://www.excelmale.com/forum/threads/nandrolone-for-mood-feeling-much-better.25165/post-222614[/URL] [HEADING=2][I][FONT=Georgia][I]Subjects and study design[/I][/FONT][/I][/HEADING] [I][I][FONT=Georgia][I]Study subjects included 27 healthy volunteers originated from the study population described in more detail elsewhere.[URL='https://www.excelmale.com/forum/javascript%3A;']14[/URL] All participants were males aged 18–50 years, with a body mass index (BMI) range of 18.2–28.7 (median value 24.3) who gave informed consent consistent with the approval of the Ethics Review Board. All subjects underwent a medical examination before enrolment to exclude any possible diseases. The participants were not taking any kind of substance that could interfere with testosterone metabolism and were tested negative for illegal drugs, AAS, HIV and hepatitis B or C. For inclusion it was also required that the subjects did not belong to the Swedish Sports Confederation nor had had a malignancy within the past five years.[/I][/FONT][/I][FONT=Georgia][I] The participants were given 500 mg testosterone enanthate as a single intramuscular dose (Testoviron®–Depot kindly provided by Schering Nordiska AB, Solna, Sweden) equivalent to 360 mg testosterone. The testosterone dose among AAS abusers varies depending on the purpose of their abuse and which other AAS they co-administrate, but most abusers report testosterone doses corresponding to 500–2000 mg testosterone enanthate/week. For safety reasons, we chose the lower dose in this range.[/I][/FONT][I][FONT=Georgia][I] Before administration, a baseline morning urine sample was collected (day 0) and morning urine was further collected on days 1 and 2. The urine samples were collected and kept refrigerated for a maximum of 48 h and then frozen at −20°C. Adverse drug reactions (ADRs) were monitored from the time of screening until day 15 after administration of testosterone. No ADRs were registered and no follow-up was needed. The study was conducted according to the Helsinki declaration and the ICH Harmonized Tripartite Guideline for Good Clinical Practice, and was approved by the Ethic Review Board, Karolinska Institutet.[/I][/FONT][/I][/I] [URL unfurl="true"]https://www.excelmale.com/forum/threads/nandrolone-for-mood-feeling-much-better.25165/post-222597[/URL] [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
TRT to Supraphysiological Levels for Body Building
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