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<blockquote data-quote="tareload" data-source="post: 215854">I understand your point and it's a good one.&nbsp; We aren't going to get any double blind studies (<a href="https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6235704/" target="_blank">RCTs</a>) to study AAS dose/cumulative dose vs outcome (insert measurement here). You can gain some insight into plausible (sometimes implausible) mechanisms from the animal/rodent literature (make sure you correct for HED) but even that is fraught with potential error.I thought the HAARLEM study posted above was decent and gives some reasonable trends:[URL unfurl=&quot;true&quot;]https://www.frontiersin.org/articles/10.3389/frph.2021.732318/full[/URL]For those that missed the above link there's some decent stuff in here:[URL unfurl=&quot;true&quot;]https://www.excelmale.com/forum/threads/microdosing-enanthate.24640/post-214827[/URL]Here's a good plot that gets into the challenge for this particular measurement:[URL unfurl=&quot;true&quot;]https://forums.t-nation.com/t/anavar-kicked-in-erection-checked-out/268112/60[/URL][URL unfurl=&quot;true&quot;]https://forums.t-nation.com/t/anavar-kicked-in-erection-checked-out/268112/61[/URL][ATTACH=full]19242[/ATTACH]At the end of the day the only thing you control is the x-axis and you are somewhere there on the plot (only one data point).&nbsp; The trend by itself makes little difference to you.</blockquote>

[QUOTE="tareload, post: 215854"] I understand your point and it's a good one. We aren't going to get any double blind studies ([URL='https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC6235704/']RCTs[/URL]) to study AAS dose/cumulative dose vs outcome (insert measurement here). You can gain some insight into plausible (sometimes implausible) mechanisms from the animal/rodent literature (make sure you correct for HED) but even that is fraught with potential error. I thought the HAARLEM study posted above was decent and gives some reasonable trends: [URL unfurl="true"]https://www.frontiersin.org/articles/10.3389/frph.2021.732318/full[/URL] For those that missed the above link there's some decent stuff in here: [URL unfurl="true"]https://www.excelmale.com/forum/threads/microdosing-enanthate.24640/post-214827[/URL] Here's a good plot that gets into the challenge for this particular measurement: [URL unfurl="true"]https://forums.t-nation.com/t/anavar-kicked-in-erection-checked-out/268112/60[/URL] [URL unfurl="true"]https://forums.t-nation.com/t/anavar-kicked-in-erection-checked-out/268112/61[/URL] [ATTACH type="full"]19242[/ATTACH] At the end of the day the only thing you control is the x-axis and you are somewhere there on the plot (only one data point). The trend by itself makes little difference to you. [/QUOTE]

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