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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
TRT and Clomid together
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<blockquote data-quote="Cataceous" data-source="post: 182448" data-attributes="member: 38109"><p>Seems to be misstated. The study cited is: <a href="https://pubmed.ncbi.nlm.nih.gov/29772111/" target="_blank">Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study</a></p><p></p><p>The three arms are 50 mg clomiphene daily, 5000 IU hCG twice weekly, or both. They find little difference between the three arms:</p><p></p><p style="margin-left: 20px"><em>In conclusion, CC alone may be an option for men with hypogonadism when maintenance of fertility is desired. Published data show that CC is a safe and efficacious drug to use as an alternative to exogenous testosterone and <strong>our data suggest it is as effective in this patient group as either hCG alone or a combination of hCG and CC</strong>.</em></p><p></p><p>So there's still no rigorous evidence showing HPTA activation when clomiphene is used with TRT. It would be expected when the TRT dosing is low enough, but most men dose well on the high side of normal.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 182448, member: 38109"] Seems to be misstated. The study cited is: [URL='https://pubmed.ncbi.nlm.nih.gov/29772111/']Clomiphene citrate and human chorionic gonadotropin are both effective in restoring testosterone in hypogonadism: a short-course randomized study[/URL] The three arms are 50 mg clomiphene daily, 5000 IU hCG twice weekly, or both. They find little difference between the three arms: [INDENT][I]In conclusion, CC alone may be an option for men with hypogonadism when maintenance of fertility is desired. Published data show that CC is a safe and efficacious drug to use as an alternative to exogenous testosterone and [B]our data suggest it is as effective in this patient group as either hCG alone or a combination of hCG and CC[/B].[/I][/INDENT] So there's still no rigorous evidence showing HPTA activation when clomiphene is used with TRT. It would be expected when the TRT dosing is low enough, but most men dose well on the high side of normal. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
TRT and Clomid together
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