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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone for Mood | Feeling much Better..
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<blockquote data-quote="JimGainz" data-source="post: 222185" data-attributes="member: 19127"><p>I have looked at dozens of such studies over the years and I can’t find one that I would put my faith in. All the studies were done either in animal models using super physiological doses, or in vitro on cell membranes and then postulating the effect. I just read one recently where they were thinking that Parkinson’s disease is more related to neuron created dopamine disorders from testosterone (endogenous not TRT) because it has a higher frequency in men - And then designed some test in a petri dish and said “aha look at how this testosterone changes the dopamine cell membranes.” Meanwhile we all know the negative effect on dopamine that low testosterone has. </p><p></p><p>From personal experience - going back to the 1980s when I was bodybuilding and steroids were legal and highly available- I can concur with negative dopamine effects - coming off the drugs created massive withdrawal symptoms. BUT - no one knew the proper way to come off - we stopped cold turkey - so no wonder we had issues. </p><p></p><p>My previous experience had me very leery of doing any androgens - let alone nandrolone. In my current protocol - I am on TRT full time - but I try to cycle the Nandrolone as best I can (16 weeks on, 4-6 weeks off) just to prove I can do it and give my body a little break. I hate this time off by the way - pain comes back fast. Also, personally, I am not concerned about brain damage or neurotoxicity effects at 100mg per week, which is my dose.</p></blockquote><p></p>
[QUOTE="JimGainz, post: 222185, member: 19127"] I have looked at dozens of such studies over the years and I can’t find one that I would put my faith in. All the studies were done either in animal models using super physiological doses, or in vitro on cell membranes and then postulating the effect. I just read one recently where they were thinking that Parkinson’s disease is more related to neuron created dopamine disorders from testosterone (endogenous not TRT) because it has a higher frequency in men - And then designed some test in a petri dish and said “aha look at how this testosterone changes the dopamine cell membranes.” Meanwhile we all know the negative effect on dopamine that low testosterone has. From personal experience - going back to the 1980s when I was bodybuilding and steroids were legal and highly available- I can concur with negative dopamine effects - coming off the drugs created massive withdrawal symptoms. BUT - no one knew the proper way to come off - we stopped cold turkey - so no wonder we had issues. My previous experience had me very leery of doing any androgens - let alone nandrolone. In my current protocol - I am on TRT full time - but I try to cycle the Nandrolone as best I can (16 weeks on, 4-6 weeks off) just to prove I can do it and give my body a little break. I hate this time off by the way - pain comes back fast. Also, personally, I am not concerned about brain damage or neurotoxicity effects at 100mg per week, which is my dose. [/QUOTE]
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Clinical Use of Anabolics and Hormones
Clinical Use of Anabolics and Hormones
Nandrolone for Mood | Feeling much Better..
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