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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
My TRT Odyssey: Lab Results and More
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<blockquote data-quote="FunkOdyssey" data-source="post: 277684" data-attributes="member: 44064"><p>I'm back with some new lab results that confirm all the worst things you've ever heard about subcutaneous injections. A month after switching to IM injections, keeping everything else the same (50 mg EOD), here's how things have changed:</p><table class='post-table ' style='width: 100%'><tr><td ><p><strong>TEST</strong></p></td><td ><p><strong>2/15/2024</strong></p></td><td ><p><strong>3/15/2024</strong></p></td><td ><p><strong>NORMAL RANGE</strong></p></td></tr><tr><td ><p>Total Testosterone</p></td><td ><p>1101 ng/dL</p></td><td ><p>1524 ng/dL</p></td><td ><p>250 - 1100 ng/dL</p></td></tr><tr><td ><p>Free T (EqD)</p></td><td ><p>166.3 pg/mL</p></td><td ><p>344.4 pg/mL</p></td><td ><p>35 - 155 pg/mL</p></td></tr><tr><td ><p>Free T (calc)</p></td><td ><p>27 ng/dL</p></td><td ><p>38.5 ng/dL</p></td><td></td></tr><tr><td ><p>SHBG</p></td><td ><p>35 nmol/L</p></td><td ><p>37 nmol/L</p></td><td ><p>10 - 50 nmol/L</p></td></tr><tr><td ><p>Estradiol</p></td><td ><p>83 pg/mL</p></td><td ><p>87 pg/mL</p></td><td ><p><= 29 pg/mL</p></td></tr><tr><td ><p>Hematocrit</p></td><td ><p>47.3%</p></td><td ><p>47.3%</p></td><td ><p>38.5 - 50%</p></td></tr><tr><td ><p>Ferritin</p></td><td ><p>28 ng/mL</p></td><td ><p>36 ng/mL</p></td><td ><p>38 - 380 ng/mL</p></td></tr></table>Both total and free T are MUCH HIGHER. All of those people you've heard say they aren't absorbing as much testosterone with SC injections? Add another to the list. What's happening to the missing SC-injected testosterone? Where does it go if it doesn't show up in the bloodstream? I have no idea. We don't have to understand the mechanism to recognize that it's a real phenomenon.</p><p></p><p>What else is apparently a real thing? More aromatization with SC injections! Look how my E2 barely budged in the face of skyrocketing total and free T. The difference in SC vs IM T/E2 ratios is exactly what Antares Pharma inadvertently documented in their first study that compared Xyosted to IM enanthate injections. It is exactly what we've heard from a ton of guys on the Internet.</p><p></p><p>We know the esterases to remove the ester from testosterone are found in interstitial fluid, all around your aromatase-laden fat tissue. It does not need to travel to the liver first. For those that haven't seen the diagram I doctored up about the fate of SC injected testosterone, here it is one more time:</p><p></p><p></p><p>[ATTACH=full]42366[/ATTACH]</p><p></p><p>Despite the absurdly high levels, I'm feeling pretty darn good, and almost exactly the same as my last update, with a couple exceptions:</p><ul> <li data-xf-list-type="ul">Sleep has been shortening. I'm waking up too early, after 5 1/2 - 6 hours, and feel wide awake. Strangely, I do not feel "wired but tired" or have any background exhaustion. I actually feel well rested and very energetic. My Oura ring is reporting good levels of deep and REM sleep. Still, I would not want to continue to get this little sleep long-term as it seems unhealthy.</li> <li data-xf-list-type="ul">Blood pressure has risen to 125-130 / 85-90. I'm not comfortable with even mildly elevated BP long-term.</li> <li data-xf-list-type="ul">Strength gains have been ridiculous. I've been scratching my head the last couple weeks after throwing up greatly increased reps on every set of every exercise.</li> </ul><p>My next move is a dose reduction. I'm going to try going back down to 40 mg EOD for 140 mg weekly. That should reduce everything by 20% if levels respond proportionately.</p><p></p><p>A couple other things I noticed:</p><ul> <li data-xf-list-type="ul">Hematocrit may have stabilized at a nice value (good).</li> <li data-xf-list-type="ul">Ferritin is starting to recover (good).</li> </ul></blockquote><p></p>
[QUOTE="FunkOdyssey, post: 277684, member: 44064"] I'm back with some new lab results that confirm all the worst things you've ever heard about subcutaneous injections. A month after switching to IM injections, keeping everything else the same (50 mg EOD), here's how things have changed: [TABLE][TR][TD] [B]TEST[/B] [/TD] [TD] [B]2/15/2024[/B] [/TD] [TD] [B]3/15/2024[/B] [/TD] [TD] [B]NORMAL RANGE[/B] [/TD][/TR] [TR][TD] Total Testosterone [/TD] [TD] 1101 ng/dL [/TD] [TD] 1524 ng/dL [/TD] [TD] 250 - 1100 ng/dL [/TD][/TR] [TR][TD] Free T (EqD) [/TD] [TD] 166.3 pg/mL [/TD] [TD] 344.4 pg/mL [/TD] [TD] 35 - 155 pg/mL [/TD][/TR] [TR][TD] Free T (calc) [/TD] [TD] 27 ng/dL [/TD] [TD] 38.5 ng/dL [/TD] [TD] [/TD][/TR] [TR][TD] SHBG [/TD] [TD] 35 nmol/L [/TD] [TD] 37 nmol/L [/TD] [TD] 10 - 50 nmol/L [/TD][/TR] [TR][TD] Estradiol [/TD] [TD] 83 pg/mL [/TD] [TD] 87 pg/mL [/TD] [TD] <= 29 pg/mL [/TD][/TR] [TR][TD] Hematocrit [/TD] [TD] 47.3% [/TD] [TD] 47.3% [/TD] [TD] 38.5 - 50% [/TD][/TR] [TR][TD] Ferritin [/TD] [TD] 28 ng/mL [/TD] [TD] 36 ng/mL [/TD] [TD] 38 - 380 ng/mL [/TD][/TR][/TABLE] Both total and free T are MUCH HIGHER. All of those people you've heard say they aren't absorbing as much testosterone with SC injections? Add another to the list. What's happening to the missing SC-injected testosterone? Where does it go if it doesn't show up in the bloodstream? I have no idea. We don't have to understand the mechanism to recognize that it's a real phenomenon. What else is apparently a real thing? More aromatization with SC injections! Look how my E2 barely budged in the face of skyrocketing total and free T. The difference in SC vs IM T/E2 ratios is exactly what Antares Pharma inadvertently documented in their first study that compared Xyosted to IM enanthate injections. It is exactly what we've heard from a ton of guys on the Internet. We know the esterases to remove the ester from testosterone are found in interstitial fluid, all around your aromatase-laden fat tissue. It does not need to travel to the liver first. For those that haven't seen the diagram I doctored up about the fate of SC injected testosterone, here it is one more time: [ATTACH type="full" alt="SC oil depot revised.jpg"]42366[/ATTACH] Despite the absurdly high levels, I'm feeling pretty darn good, and almost exactly the same as my last update, with a couple exceptions: [LIST] [*]Sleep has been shortening. I'm waking up too early, after 5 1/2 - 6 hours, and feel wide awake. Strangely, I do not feel "wired but tired" or have any background exhaustion. I actually feel well rested and very energetic. My Oura ring is reporting good levels of deep and REM sleep. Still, I would not want to continue to get this little sleep long-term as it seems unhealthy. [*]Blood pressure has risen to 125-130 / 85-90. I'm not comfortable with even mildly elevated BP long-term. [*]Strength gains have been ridiculous. I've been scratching my head the last couple weeks after throwing up greatly increased reps on every set of every exercise. [/LIST] My next move is a dose reduction. I'm going to try going back down to 40 mg EOD for 140 mg weekly. That should reduce everything by 20% if levels respond proportionately. A couple other things I noticed: [LIST] [*]Hematocrit may have stabilized at a nice value (good). [*]Ferritin is starting to recover (good). [/LIST] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
My TRT Odyssey: Lab Results and More
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