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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
How to co relate RIA and equilibrium dialysis reports
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<blockquote data-quote="Cataceous" data-source="post: 279006" data-attributes="member: 38109"><p>They're saying that the RIA method they tested gives numbers that are a factor of seven smaller than the results from equilibrium dialysis. So arguably RIA is measuring some parameter that correlates well with actual free testosterone, but you have to multiply by seven to get the correct estimate for free testosterone. You can somewhat see this in play with your own measurement. The units are pg/mL, and 10 pg/mL = 1 ng/dL. Your value of 49 pg/mL is 4.9 ng/dL, which would be low, considering that free testosterone is on the order of two percent of total testosterone. So clearly at a minimum some multiplicative factor must be applied to put the absolute numbers closer to reality. Since you don't know the correction factor for this test you can only rely on the reference range. Calculated free testosterone avoids a lot of this complexity, because different assays for total testosterone and SHBG don't vary as severely as those for free testosterone do.</p></blockquote><p></p>
[QUOTE="Cataceous, post: 279006, member: 38109"] They're saying that the RIA method they tested gives numbers that are a factor of seven smaller than the results from equilibrium dialysis. So arguably RIA is measuring some parameter that correlates well with actual free testosterone, but you have to multiply by seven to get the correct estimate for free testosterone. You can somewhat see this in play with your own measurement. The units are pg/mL, and 10 pg/mL = 1 ng/dL. Your value of 49 pg/mL is 4.9 ng/dL, which would be low, considering that free testosterone is on the order of two percent of total testosterone. So clearly at a minimum some multiplicative factor must be applied to put the absolute numbers closer to reality. Since you don't know the correction factor for this test you can only rely on the reference range. Calculated free testosterone avoids a lot of this complexity, because different assays for total testosterone and SHBG don't vary as severely as those for free testosterone do. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Blood Test Discussion
How to co relate RIA and equilibrium dialysis reports
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