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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How long do I have to wait to re-test e2 after changing arimidex doseage?
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<blockquote data-quote="Someguy" data-source="post: 17498" data-attributes="member: 2736"><p>Sorry to keep replying to myself. I may have answered my own question. According to Dr. Google, steady state of a drug is achieved after 4-5 half-lives, and frequency of administration doesn't affect the time to reach steady state.</p><p></p><p>So, assuming I'm not missing anything I can figure out when my e2 will be at it's new stable level after changing doses by calculating the time for arimidex to reach it's new steady state, plus the time for estradiol left over from the old arimidex level to be eliminated:</p><p></p><p></p><p>Arimidex half-life of 46.8 hours x 5 half-lives = 234 hours to reach steady state</p><p></p><p>Estradiol half-life of 15 hours x 5 half-lives = 75 hours to eliminate leftover estradiol.</p><p></p><p>234 hours + 75 hours = <strong>309 hours, or around 13 days.</strong></p><p></p><p>Does all of that seem correct? Based on the above it seems to me that I'd be pretty safe re-testing e2 levels 2 weeks after changing dosages. Thoughts?</p></blockquote><p></p>
[QUOTE="Someguy, post: 17498, member: 2736"] Sorry to keep replying to myself. I may have answered my own question. According to Dr. Google, steady state of a drug is achieved after 4-5 half-lives, and frequency of administration doesn't affect the time to reach steady state. So, assuming I'm not missing anything I can figure out when my e2 will be at it's new stable level after changing doses by calculating the time for arimidex to reach it's new steady state, plus the time for estradiol left over from the old arimidex level to be eliminated: Arimidex half-life of 46.8 hours x 5 half-lives = 234 hours to reach steady state Estradiol half-life of 15 hours x 5 half-lives = 75 hours to eliminate leftover estradiol. 234 hours + 75 hours = [B]309 hours, or around 13 days.[/B] Does all of that seem correct? Based on the above it seems to me that I'd be pretty safe re-testing e2 levels 2 weeks after changing dosages. Thoughts? [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
How long do I have to wait to re-test e2 after changing arimidex doseage?
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