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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
HELP - Doubts about TRT
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<blockquote data-quote="Phil Goodman" data-source="post: 279082" data-attributes="member: 42777"><p>Differences in SHBG could explain differences in free t, but wouldn’t necessarily explain differences in total. Also, you seem to imply that differences in protocols explain the rest of the differences with regard to varying measurements(ie measuring the trough of a 3 times/week vs trough of 1 time/week). And I’m sure you are right that it can explain some of the differences, but it very very likely doesn’t explain it all as differences between one person to the next can be vast. So unless you have studies which show people at the same weights on the same protocols got extremely similar readings of total t then it is reasonable to say that differences in people also results in differences of processing exogenous testosterone.</p><p></p><p></p><p></p><p>As far as the burden of proof, according to you I’ve been operating at “supra-physiological” ranges for three years with frequent blood tests and my labs are better than ever. I also feel great and am more productive with better well-being than when operating at what you would call “normal” levels. Sure that’s only an N=1 account, but for me that’s the most important N. And there are tons of guys in my same boat. Obviously there are risks involved, just as there are risks with everything(including living with low, what you would call “normal”, testosterone levels). People often try to find a path where they can say “this is the correct path and that’s the incorrect path” so that things are cut and dry. But that’s not how the world, or humans, operate. Instead every decision is a trade off that involves both positives and negatives. So optimizing your path through life really means making decisions with the best tradeoffs. All I’m saying is that for some people, that tradeoff may involve taking what you would call “Supra-physiological” doses of testosterone. Obviously there is a point where the tradeoff becomes a net negative, but again that can be different for different people.</p></blockquote><p></p>
[QUOTE="Phil Goodman, post: 279082, member: 42777"] Differences in SHBG could explain differences in free t, but wouldn’t necessarily explain differences in total. Also, you seem to imply that differences in protocols explain the rest of the differences with regard to varying measurements(ie measuring the trough of a 3 times/week vs trough of 1 time/week). And I’m sure you are right that it can explain some of the differences, but it very very likely doesn’t explain it all as differences between one person to the next can be vast. So unless you have studies which show people at the same weights on the same protocols got extremely similar readings of total t then it is reasonable to say that differences in people also results in differences of processing exogenous testosterone. As far as the burden of proof, according to you I’ve been operating at “supra-physiological” ranges for three years with frequent blood tests and my labs are better than ever. I also feel great and am more productive with better well-being than when operating at what you would call “normal” levels. Sure that’s only an N=1 account, but for me that’s the most important N. And there are tons of guys in my same boat. Obviously there are risks involved, just as there are risks with everything(including living with low, what you would call “normal”, testosterone levels). People often try to find a path where they can say “this is the correct path and that’s the incorrect path” so that things are cut and dry. But that’s not how the world, or humans, operate. Instead every decision is a trade off that involves both positives and negatives. So optimizing your path through life really means making decisions with the best tradeoffs. All I’m saying is that for some people, that tradeoff may involve taking what you would call “Supra-physiological” doses of testosterone. Obviously there is a point where the tradeoff becomes a net negative, but again that can be different for different people. [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Basics & Questions
HELP - Doubts about TRT
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