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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
hCG and Vision
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<blockquote data-quote="Nelson Vergel" data-source="post: 9722" data-attributes="member: 3"><p>HCG may actually lower intraocular (inside the eye) pressure that is usually high in glaucoma. Pregnant women's bodies produce a lot of HCG. They have seen stable or improved eye pressure in women with glaucoma who are pregnant.</p><p></p><p>[h=4]hCG and Ocular Pressure[/b]It has been shown for many years that hCG injection lowers intraocular pressure (IOP) in rabbit<a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Putterman1" target="_blank">[51]</a>, <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Elman1" target="_blank">[52]</a>. The mechanism of action was unknown and LHR was not yet identified within the retina, therefore some authors suggested that hCG action was due to a purity artifact as the results were not mimics by the LH <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Liu1" target="_blank">[53]</a>. However intraventricular, but not intravenous injection, of gonadotropin releasing hormone mimic the IOP decrease <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Liu2" target="_blank">[54]</a>, demonstrating the specificity of hCG action in this mechanism. Interestingly pregnancy is usually associated with relatively lower IOP, but the mechanism of action is not yet identified <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Ziai1" target="_blank">[55]</a>, <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Efe1" target="_blank">[56]</a>. In women with preexisting glaucoma condition, IOP remain stable despite a reduction in the number of hypotensive agents during pregnancy <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-MendezHernandez1" target="_blank">[57]</a>. Gonadotropin injection may therefore consist in a pressure lowering agent in the treatment of glaucomatous pathologies as suggested many years ago <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Gierkowa1" target="_blank">[58]</a>, <a href="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Kass1" target="_blank">[59]</a>. Further study on the localization of LHR receptor within the structures involved in the regulation of ocular pressure (ciliary body, trabecular meshwork and vasculature) would help to decipher the cascade of events leading to IOP reduction."</p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 9722, member: 3"] HCG may actually lower intraocular (inside the eye) pressure that is usually high in glaucoma. Pregnant women's bodies produce a lot of HCG. They have seen stable or improved eye pressure in women with glaucoma who are pregnant. [h=4]hCG and Ocular Pressure[/b]It has been shown for many years that hCG injection lowers intraocular pressure (IOP) in rabbit[URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Putterman1"][51][/URL], [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Elman1"][52][/URL]. The mechanism of action was unknown and LHR was not yet identified within the retina, therefore some authors suggested that hCG action was due to a purity artifact as the results were not mimics by the LH [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Liu1"][53][/URL]. However intraventricular, but not intravenous injection, of gonadotropin releasing hormone mimic the IOP decrease [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Liu2"][54][/URL], demonstrating the specificity of hCG action in this mechanism. Interestingly pregnancy is usually associated with relatively lower IOP, but the mechanism of action is not yet identified [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Ziai1"][55][/URL], [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Efe1"][56][/URL]. In women with preexisting glaucoma condition, IOP remain stable despite a reduction in the number of hypotensive agents during pregnancy [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-MendezHernandez1"][57][/URL]. Gonadotropin injection may therefore consist in a pressure lowering agent in the treatment of glaucomatous pathologies as suggested many years ago [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Gierkowa1"][58][/URL], [URL="http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052567#pone.0052567-Kass1"][59][/URL]. Further study on the localization of LHR receptor within the structures involved in the regulation of ocular pressure (ciliary body, trabecular meshwork and vasculature) would help to decipher the cascade of events leading to IOP reduction." [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
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