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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Estradiol blunts muscle damage induced by exercise
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<blockquote data-quote="Nelson Vergel" data-source="post: 35036" data-attributes="member: 3"><p><strong>The influence of estradiol on muscle damage and leg strength after intense eccentric exercise.</strong></p><p></p><p></p><p>Minahan C, et al. </p><p></p><p>Eur J Appl Physiol. 2015.</p><p></p><p></p><p></p><p>Abstract</p><p></p><p>PURPOSE: To examine the influence of estradiol on muscle damage and leg strength after intense eccentric exercise.</p><p></p><p>METHODS: Eight men (MEN), eight normally menstruating women (WomenNM), and eight women using oral contraceptives (WomenOC) participated in this study. Subjects performed 240 maximal-effort bilateral eccentric contractions of the quadriceps muscle groups designed to elicit exercise-induced muscle damage (EiMD). Serum creatine kinase (CK), myoglobin (Mb), and fatty acid-binding protein (FABP) concentrations were measured before (pre-) EiMD, as well as 0, 6, 24, and 48 h post-EiMD. Peak isometric quadriceps torque (i.e., leg strength) was measured pre-EiMD, as well as 24 and 48 h post-EiMD.</p><p></p><p>RESULTS: The increases in CK, Mb, and FABP concentrations from pre- to post-EiMD were greater in MEN (10-fold, 15-fold, and fourfold, respectively) and WomenOC (sevenfold, 11-fold, and ninefold) compared with WomenNM (five-, six-, and threefold; p < 0.05). The decline in leg strength was about 10 % pre- to 24 h post-EiMD in all groups and decreased a further 10-15 % by 48 h post-EiMD in the MEN and WomenOC only.</p><p></p><p>CONCLUSION:<strong> Our findings suggest an important role of estradiol in blunting the muscle damage response to intense eccentric exercise and preserving muscle function after EiMD.</strong></p></blockquote><p></p>
[QUOTE="Nelson Vergel, post: 35036, member: 3"] [B]The influence of estradiol on muscle damage and leg strength after intense eccentric exercise.[/B] Minahan C, et al. Eur J Appl Physiol. 2015. Abstract PURPOSE: To examine the influence of estradiol on muscle damage and leg strength after intense eccentric exercise. METHODS: Eight men (MEN), eight normally menstruating women (WomenNM), and eight women using oral contraceptives (WomenOC) participated in this study. Subjects performed 240 maximal-effort bilateral eccentric contractions of the quadriceps muscle groups designed to elicit exercise-induced muscle damage (EiMD). Serum creatine kinase (CK), myoglobin (Mb), and fatty acid-binding protein (FABP) concentrations were measured before (pre-) EiMD, as well as 0, 6, 24, and 48 h post-EiMD. Peak isometric quadriceps torque (i.e., leg strength) was measured pre-EiMD, as well as 24 and 48 h post-EiMD. RESULTS: The increases in CK, Mb, and FABP concentrations from pre- to post-EiMD were greater in MEN (10-fold, 15-fold, and fourfold, respectively) and WomenOC (sevenfold, 11-fold, and ninefold) compared with WomenNM (five-, six-, and threefold; p < 0.05). The decline in leg strength was about 10 % pre- to 24 h post-EiMD in all groups and decreased a further 10-15 % by 48 h post-EiMD in the MEN and WomenOC only. CONCLUSION:[B] Our findings suggest an important role of estradiol in blunting the muscle damage response to intense eccentric exercise and preserving muscle function after EiMD.[/B] [/QUOTE]
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Testosterone Replacement, Low T, HCG, & Beyond
Testosterone Side Effect Management
Estradiol blunts muscle damage induced by exercise
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